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EEG/MEG source imaging of deep brain activity within the maximum entropy on the mean framework: Simulations and validation in epilepsy

Author(s): Afnan J; Cai Z; Lina JM; Abdallah C; Delaire E; Avigdor T; Ros V; Hedrich T; von Ellenrieder N; Kobayashi E; Frauscher B; Gotman J; Grova C;

Electro/Magneto-EncephaloGraphy (EEG/MEG) source imaging (EMSI) of epileptic activity from deep generators is often challenging due to the higher sensitivity of EEG/MEG to superficial regions and to the spatial configuration of subcortical structures. We previously demonstrated the ability of the ...

Article GUID: 38994740


Validating MEG source imaging of resting state oscillatory patterns with an intracranial EEG atlas

Author(s): Afnan J; von Ellenrieder N; Lina JM; Pellegrino G; Arcara G; Cai Z; Hedrich T; Abdallah C; Khajehpour H; Frauscher B; Gotman J; Grova C;

Background: Magnetoencephalography (MEG) is a widely used non-invasive tool to estimate brain activity with high temporal resolution. However, due to the ill-posed nature of the MEG source imaging (MSI) problem, the ability of MSI to identify accurately underlying brain sources along the cortical ...

Article GUID: 37149236


Hierarchical Bayesian modeling of the relationship between task-related hemodynamic responses and cortical excitability

Author(s): Cai Z; Pellegrino G; Lina JM; Benali H; Grova C;

Investigating the relationship between task-related hemodynamic responses and cortical excitability is challenging because it requires simultaneous measurement of hemodynamic responses while applying noninvasive brain stimulation. Moreover, cortical excitability and task-related hemodynamic responses are both associated with inter-/intra-subject variabili ...

Article GUID: 36250709


Evaluation of a personalized functional near infra-red optical tomography workflow using maximum entropy on the mean

Author(s): Cai Z; Uji M; Aydin Ü; Pellegrino G; Spilkin A; Delaire É; Abdallah C; Lina JM; Grova C;

In the present study, we proposed and evaluated a workflow of personalized near infra-red optical tomography (NIROT) using functional near-infrared spectroscopy (fNIRS) for spatiotemporal imaging of cortical hemodynamic fluctuations. The proposed workflow from fNIRS data acquisition to local 3D reconstruction consists of: (a) the personalized optimal mont ...

Article GUID: 34342073


Data-driven beamforming technique to attenuate ballistocardiogram artefacts in electroencephalography-functional magnetic resonance imaging without detecting cardiac pulses in electrocardiography recordings

Author(s): Uji M; Cross N; Pomares FB; Perrault AA; Jegou A; Nguyen A; Aydin U; Lina JM; Dang-Vu TT; Grova C;

Simultaneous recording of electroencephalography (EEG) and functional magnetic resonance imaging (fMRI) is a very promising non-invasive neuroimaging technique. However, EEG data obtained from the simultaneous EEG-fMRI are strongly influenced by MRI-related artefacts, namely gradient artefacts (G ...

Article GUID: 34101939


How cerebral cortex protects itself from interictal spikes: The alpha/beta inhibition mechanism

Author(s): Pellegrino G; Hedrich T; Sziklas V; Lina JM; Grova C; Kobayashi E;

Interactions between interictal epileptiform discharges (IEDs) and distant cortical regions subserve potential effects on cognition of patients with focal epilepsy. We hypothesize that "healthy" brain areas at a distance from the epileptic focus may respond to the interference of IEDs by generating inhibitory alpha and beta oscillations. We predict that m ...

Article GUID: 34002916


Deconvolution of hemodynamic responses along the cortical surface using personalized functional near infrared spectroscopy

Author(s): Machado A; Cai Z; Vincent T; Pellegrino G; Lina JM; Kobayashi E; Grova C;

In functional near infrared spectroscopy (fNIRS), deconvolution analysis of oxy and deoxy-hemoglobin concentration changes allows estimating specific hemodynamic response functions (HRF) elicited by neuronal activity, taking advantage of the fNIRS excellent temporal resolution. Diffuse optical tomography (DOT) is also becoming the new standard reconstruct ...

Article GUID: 33727581


Effects of Independent Component Analysis on Magnetoencephalography Source Localization in Pre-surgical Frontal Lobe Epilepsy Patients

Author(s): Pellegrino G, Xu M, Alkuwaiti A, Porras-Bettancourt M, Abbas G, Lina JM, Grova C, Kobayashi E,

Objective: Magnetoencephalography source imaging (MSI) of interictal epileptiform discharges (IED) is a useful presurgical tool in the evaluation of drug-resistant frontal lobe epilepsy (FLE) patients. Yet, failures in MSI can arise related to artifacts and to interference of background activity. ...

Article GUID: 32582009


Accuracy and spatial properties of distributed magnetic source imaging techniques in the investigation of focal epilepsy patients.

Author(s): Pellegrino G, Hedrich T, Porras-Bettancourt M, Lina JM, Aydin Ü, Hall J, Grova C, Kobayashi E

Hum Brain Mapp. 2020 May 09;: Authors: Pellegrino G, Hedrich T, Porras-Bettancourt M, Lina JM, Aydin Ü, Hall J, Grova C, Kobayashi E

Article GUID: 32386115


Magnetoencephalography resting state connectivity patterns as indicatives of surgical outcome in epilepsy patients.

Author(s): Aydin Ü, Pellegrino G, Bin Ka'b Ali O, Abdallah C, Dubeau F, Lina JM, Kobayashi E, Grova C

J Neural Eng. 2020 Mar 18;: Authors: Aydin Ü, Pellegrino G, Bin Ka'b Ali O, Abdallah C, Dubeau F, Lina JM, Kobayashi E, Grova C

Article GUID: 32191632


Differences in MEG and EEG power-law scaling explained by a coupling between spatial coherence and frequency: a simulation study.

Author(s): Bénar CG, Grova C, Jirsa VK, Lina JM

J Comput Neurosci. 2019 Jul 11;: Authors: Bénar CG, Grova C, Jirsa VK, Lina JM

Article GUID: 31292816


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