Author(s): Li W; Feng Y; Feng Z; Wang L; Whiteway M; Lu H; Jiang Y;

Fluconazole (FLC) is extensively employed for the prophylaxis and treatment of invasive fungal infections (IFIs). However, the fungistatic nature of FLC renders pathogenic fungi capable of developing tolerance towards it. Consequently, converting FLC into a fungicidal agent using adjuvants assumes significance to circumvent FLC resistance and the perpetua ...

Article GUID: 38929106

Author(s): Lu H; Li W; Whiteway M; Wang H; Zhu S; Ji Z; Feng Y; Yan L; Fang T; Li L; Ni T; Zhang X; Lv Q; Ding Z; Qiu L; Zhang D; Jiang Y;

Fluconazole (FLC) is widely used to prevent and treat invasive fungal infections. However, FLC is a fungistatic agent, allowing clinical FLC-susceptible isolates to tolerate FLC. Making FLC fungicidal in combination with adjuvants is a promising strategy to avoid FLC resistance and eliminate the ...

Article GUID: 36475771

Author(s): Liu Q; Li L; Zhang X; Saini A; Li W; Hung H; Hao C; Li K; Lee P; Wentzell JJB; Huo C; Li SM; Harner T; Liggio J;

Commercial chemicals are used extensively across urban centres worldwide1, posing a potential exposure risk to 4.2 billion people2. Harmful chemicals are often assessed on the basis of their environmental persistence, accumulation in biological organisms and toxic properties, under international ...

Article GUID: 34912090

Author(s): Li W; Shrivastava M; Lu H; Jiang Y;

Increased morbidity and mortality of candidiasis are a notable threat to the immunocompromised patients. At present, the types of drugs available to treat C. albicans infection are relatively limited. Moreover, the emergence of antifungal drug resistance of C. albicans makes the treatment of C. albicans infection more difficult. The calcium-calcineurin si ...

Article GUID: 33989979

Author(s): Luo B, Huang G, Yao Y, An C, Li W, Zheng R, Zhao K

Sulfonamide antibiotics have highly toxic effects on humans and other organisms within the food chain. Adsorption by various carbonaceous materials is an effective method for removing them from the aqueous environment. Batch adsorption experiments were conducted between adsorbents and sulfamethoxazole (SMX) by studies of characterization, isotherm model, ...

Article GUID: 32886308

Author(s): Dragomir AI, Boucher VG, Bacon SL, Gemme C, Szczepanik G, Corace K, Campbell TS, Vallis MT, Garber G, Rouleau C, Rabi D, Diodati JG, Ghali W, Lavoie KL

Transl Behav Med. 2020 Mar 07;: Authors: Dragomir AI, Boucher VG, Bacon SL, Gemme C, Szczepanik G, Corace K, Campbell TS, Vallis MT, Garber G, Rouleau C, Rabi D, Diodati JG, Ghali W, Lavoie KL

Article GUID: 32145022