Author(s): Thombs BD; Levis AW; Azar M; Saadat N; Riehm KE; Sanchez TA; Chiovitti MJ; Rice DB; Levis B; Fedoruk C; Lyubenova A; Malo Vázquez de Lara AL; Kloda LA; Benedetti A; Shrier I; Platt RW; Kimmelman J;

Objectives: We evaluated whether sample sizes in different arms of two-arm parallel group randomized controlled trials of nonregulated interventions were systematically closer in size than would plausibly occur by chance if simple randomization had been applied. Study design and setting: We sear ...

Article GUID: 31866472

Author(s): Wu Y; Levis B; Riehm KE; Saadat N; Levis AW; Azar M; Rice DB; Boruff J; Cuijpers P; Gilbody S; Ioannidis JPA; Kloda LA; McMillan D; Patten SB; Shrier I; Ziegelstein RC; Akena DH; Arroll B; Ayalon L; Baradaran HR; Baron M; Bombardier CH; ...

Background: Item 9 of the Patient Health Questionnaire-9 (PHQ-9) queries about thoughts of death and self-harm, but not suicidality. Although it is sometimes used to assess suicide risk, most positive responses are not associated with suicidality. The PHQ-8, which omits Item 9, is thus increasing ...

Article GUID: 31298180

Author(s): Levis B; Benedetti A; Riehm KE; Saadat N; Levis AW; Azar M; Rice DB; Chiovitti MJ; Sanchez TA; Cuijpers P; Gilbody S; Ioannidis JPA; Kloda LA; McMillan D; Patten SB; Shrier I; Steele RJ; Ziegelstein RC; Akena DH; Arroll B; Ayalon L; Bara ...

Background: Different diagnostic interviews are used as reference standards for major depression classification in research. Semi-structured interviews involve clinical judgement, whereas fully structured interviews are completely scripted. The Mini International Neuropsychiatric Interview (MINI) ...

Article GUID: 29717691

Author(s): Ishihara M; Harel D; Levis B; Levis AW; Riehm KE; Saadat N; Azar M; Rice DB; Sanchez TA; Chiovitti MJ; Cuijpers P; Gilbody S; Ioannidis JPA; Kloda LA; McMillan D; Patten SB; Shrier I; Arroll B; Bombardier CH; Butterworth P; Carter G; Clo ...

Background: The objective of this study was to develop and validate a short form of the Patient Health Questionnaire-9 (PHQ-9), a self-report questionnaire for assessing depressive symptomatology, using objective criteria. Methods: Responses on the PHQ-9 were obtained from 7,850 English-speaking ...

Article GUID: 30238571

Author(s): Azar M; Riehm KE; Saadat N; Sanchez T; Chiovitti M; Qi L; Rice DB; Levis B; Fedoruk C; Levis AW; Kloda LA; Kimmelman J; Benedetti A; Thombs BD;

Importance: Many interventions that are important to the health care of patients are not subject to regulation by the US Food and Drug Administration (FDA) or comparable regulatory bodies in other nations. Objective: To determine whether specialty journals that publish trials of primarily nonreg ...

Article GUID: 30855655