1 Department of Health, Kinesiology, and Applied Physiology, Concordia University, and Montréal Behavioural Medicine Centre, CIUSSS-NIM, Hôpital du Sacré-Coeur de Montréal, Montréal, Quebec, Canada.
2 Faculty of Nutrition Sciences and Food Technology, Department of Clinical Nutrition & Dietetics, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
3 Faculty of Biostatistics, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
4 Vice-Chancellery of Food and Drug, Shahroud University of Medical Sciences, Shahroud, Iran.
5 Drug Applied Research Center, School of Pharmacy, Tabriz University of Medical Sciences, Tabriz, Iran.
6 Faculty of Nutrition Science and Food Technology, Department of Cellular and Molecular Nutrition, Shahid Beheshti University of Medical Sciences, Tehran, Iran.

Grape seed extract supplementation along with a restricted-calorie diet improves cardiovascular risk factors in obese or overweight adult individuals: A randomized, placebo-controlled trial.

Phytother Res. 2020 Oct 12; :

Authors: Yousefi R, Parandoosh M, Khorsandi H, Hosseinzadeh N, Madani Tonekaboni M, Saidpour A, Babaei H, Ghorbani A

Abstract

Grape seed extract (GSE) is a flavonoid-rich supplement, recently discussed as a potential moderator of inflammation and obesity. In this study, we aimed to investigate the effects of GSE supplementation along with a restricted-calorie diet (RCD), on changes in blood lipid profile, visceral adiposity index (VAI), and atherogenic index of plasma (AIP). We designed a randomized, double-blinded, placebo-controlled clinical trial. Forty obese or overweight individuals (25?=?body mass index?

PMID: 33044768 [PubMed - as supplied by publisher]