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Roles of inter- and intramolecular tryptophan interactions in membrane-active proteins revealed by racemic protein crystallography

Author(s): Lander AJ; Mercado LD; Li X; Taily IM; Findlay BL; Jin Y; Luk LYP;

Tryptophan is frequently found on the surface of membrane-associated proteins that interact with the lipid membrane. However, because of their multifaceted interactions, it is difficult to pinpoint the structure-activity relationship of each tryptophan residue. Here, we describe the use of racemic protein crystallography to probe dedicated tryptophan inte ...

Article GUID: 37464011


Proteomics-based vaccine targets annotation and design of subunit and mRNA-based vaccines for Monkeypox virus (MPXV) against the recent outbreak

Author(s): Jin Y; Fayyaz A; Liaqat A; Khan A; Alshammari A; Wang Y; Gu RX; Wei DQ;

Monkeypox Virus (MPXV) is a growing public health threat with increasing cases and fatalities globally. To date, no specific vaccine or small molecule therapeutic choices are available for the treatment of MPXV disease. In this work, we employed proteomics and structural vaccinology approaches to design mRNA and multi-epitopes-based vaccines (MVC) against ...

Article GUID: 37116237


Distributed adaptive fault-tolerant close formation flight control of multiple trailing fixed-wing UAVs.

Author(s): Yu Z, Zhang Y, Jiang B, Yu X, Fu J, Jin Y, Chai T

ISA Trans. 2020 Jul 09;: Authors: Yu Z, Zhang Y, Jiang B, Yu X, Fu J, Jin Y, Chai T

Article GUID: 32680604


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