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Sex-specific effects of intensity and dose of physical activity on BOLD-fMRI cerebrovascular reactivity and cerebral pulsatility

Author(s): Potvin-Jutras Z; Intzandt B; Mohammadi H; Liu P; Chen JJ; Gauthier CJ;

Cerebrovascular reactivity (CVR) and cerebral pulsatility (CP) are important indicators of cerebrovascular health and have been shown to be associated with physical activity (PA). Sex differences have been shown to influence the impact of PA on cerebrovascular health. However, the sex-specific effects of PA on CP and CVR, particularly in relation to inten ...

Article GUID: 39416007


Multiple routes to help you roam: A comparison of training interventions to improve cognitive-motor dual-tasking in healthy older adults

Author(s): Downey R; Bherer L; Pothier K; Vrinceanu T; Intzandt B; Berryman N; Lussier M; Vincent T; Karelis AD; Nigam A; Vu TTM; Bosquet L; Li KZH;

Cognitive-motor dual-tasking is a complex activity that predicts falls risk and cognitive impairment in older adults. Cognitive and physical training can both lead to improvements in dual-tasking; however, less is known about what mechanisms underlie these changes. To investigate this, 33 healthy ...

Article GUID: 36408116


Mastering the Relationship between the Body and the Brain? The Case of a Female Master Athlete

Author(s): Saillant K; Intzandt B; Bérubé B; Sanami S; Gauthier C; Bherer L;

Background: Physical inactivity significantly increases risk of cardiovascular diseases, which are highly prevalent in aging. Conversely, higher levels of physical activity in aging have been associated with benefits for physical and cognitive health and is hypothesized to prevent and reduce development of cardiovascular risk factors. However, those older ...

Article GUID: 35950796


A comparison of the effect of physical activity and cognitive training on dual-task performance in older adults

Author(s): Vrinceanu T; Blanchette CA; Intzandt B; Lussier M; Pothier K; Vu TTM; Nigam A; Bosquet L; Karelis AD; Li KZH; Berryman N; Bherer L;

Objectives: Studies suggest that cognitive training and physical activity can improve age-related deficits in dual-task performances. However, both of these interventions have never been compared in the same study. This paper investigates the improvement in dual-task performance in two types of e ...

Article GUID: 34865009


Sex moderations in the relationship between aortic stiffness, cognition, and cerebrovascular reactivity in healthy older adults

Author(s): Sabra D; Intzandt B; Desjardins-Crepeau L; Langeard A; Steele CJ; Frouin F; Hoge RD; Bherer L; Gauthier CJ;

It is well established that sex differences exist in the manifestation of vascular diseases. Arterial stiffness (AS) has been associated with changes in cerebrovascular reactivity (CVR) and cognitive decline in aging. Specifically, older adults with increased AS show a decline on executive functi ...

Article GUID: 34582484


Comparing the effect of Cognitive vs. Exercise Training on brain MRI outcomes in healthy older adults: A systematic review

Author(s): Intzandt B; Vrinceanu T; Huck J; Vincent T; Montero-Odasso M; Gauthier CJ; Bherer L;

Aging is associated with cognitive decline. Importantly cognition and cerebral health is enhanced with interventions like cognitive (CT) and exercise training (ET). However, effects of CT and ET interventions on brain magnetic resonance imaging outcomes have never been compared systematically. Here, the primary objective was to critically and systematical ...

Article GUID: 34245760


A comparison of physical exercise and cognitive training interventions to improve determinants of functional mobility in healthy older adults

Author(s): Pothier K; Vrinceanu T; Intzandt B; Bosquet L; Karelis AD; Lussier M; Vu TTM; Nigam A; Li KZH; Berryman N; Bherer L;

Objectives: Mobility is a complex but crucial clinical outcome in older adults. Past observational studies have highlighted that cardiorespiratory fitness (CRF), energy cost of walking (ECW), and cognitive switching abilities are associated with mobility performance, making these key determinants ...

Article GUID: 33774144


Higher cardiovascular fitness level is associated with lower cerebrovascular reactivity and perfusion in healthy older adults.

Author(s): Intzandt B, Sabra D, Foster C, Desjardins-Crépeau L, Hoge RD, Steele CJ, Bherer L, Gauthier CJ

J Cereb Blood Flow Metab. 2019 Jul 25;:271678X19862873 Authors: Intzandt B, Sabra D, Foster C, Desjardins-Crépeau L, Hoge RD, Steele CJ, Bherer L, Gauthier CJ

Article GUID: 31342831


The effects of exercise on cognition and gait in Parkinson's disease: A scoping review.

Author(s): Intzandt B, Beck EN, Silveira CRA

Neurosci Biobehav Rev. 2018 12;95:136-169 Authors: Intzandt B, Beck EN, Silveira CRA

Article GUID: 30291852


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