Author(s): Gohari MH; Ghamari P; Hamzehpoor E; Effaty F; Frišcic T; Perepichka DF;

We report that mechanochemistry enables the synthesis of new p-conjugated covalent organic frameworks (COFs) based on naphthotetrathiophenetetracarbaldehydes 2TTN and 3TTN, expanding the scope of COF structures with two new isomeric tetradentate nodes. While recent studies have explored COF isomerism by varying bidentate linkers to tune electronic propert ...

Article GUID: 40936612

Author(s): Zhang Y; Al-Mahayni H; Aguiar PM; Chartrand D; McKee M; Shamekhi M; Seifitokaldani A; Kornienko N;

Co-electrolysis of CO2 with simple N-species is an appealing route to sustainable fabrication of C-N bond containing products. A prominent challenge in this direction is to promote the C-N coupling step in place of the established CO2 reduction pathways. This can be particularly difficult when re ...

Article GUID: 40883279

Author(s): Zou H; Wang Y; Huang A;

Fine-grained aspect-based sentiment analysis requires language models to identify aspect entities and the corresponding sentiment information in the input text content. Transformer-based pre-trained large language models have demonstrated remarkable performance on various challenging natural language processing tasks. However, large language models face l ...

Article GUID: 40876298

Author(s): Villeneuve S; Poirier J; Breitner JCS; Tremblay-Mercier J; Remz J; Raoult JM; Yakoub Y; Gallego-Rudolf J; Qiu T; Valdez AF; Mohammediyan B; Javanray M; Metz A; Sanami S; Ourry V; Wearn A; Pastor-Bernier A; Edde M; Gonneaud J; Strikwerda- ...

The PREVENT-AD is an investigator-driven study that was created in 2011 and enrolled cognitively normal older adults with a family history of sporadic AD. Participants are deeply phenotyped and have now been followed annually for more than 12 years [median follow-up 8.0 years,SD 3.1]. Multimodal ...

Article GUID: 40778177

Author(s): Carter F; Hobishi H; Chapman CA;

The parasubiculum is a component of the hippocampal formation that projects to the entorhinal cortex and plays an important role in spatial navigation. Dopamine has marked effects on excitatory synaptic transmission in the hippocampus and entorhinal cortex, and the present study investigated the effects of dopamine on evoked field excitatory postsynaptic ...

Article GUID: 40818632

Author(s): Patel MA; Boribong BP; Sinha H; Xiao B; Xie K; Vo PQN; Chin AB; Ellouzi A; Little SR; Shih S; Wu H; Muller WJ; Hirukawa A;

High-efficiency gene editing in primary human cells is critical for advancing therapeutic development and functional genomics, yet conventional electroporation platforms often require high cell input and are poorly suited to parallelized experiments. Here we introduce a next-generation digital mi ...

Article GUID: 40790054

Author(s): Koleilat T; Asgariandehkordi H; Rivaz H; Xiao Y;

Segmentation of anatomical structures and pathologies in medical images is essential for modern disease diagnosis, clinical research, and treatment planning. While significant advancements have been made in deep learning-based segmentation techniques, many of these methods still suffer from limitations in data efficiency, generalizability, and interactivi ...

Article GUID: 40779830

Author(s): Hu Y; Su H; Fu J; Luo J; Yu Q; Zhao F; Li W; Deng S; Liu Y; Yuan Y; Gan Y; Wang Y; Kim JT; Chen N; Shakouri M; Hao X; Gao Y; Pang T; Zhang N; Jiang M; Li X; Zhao Y; Tu J; Wang C; Sun X;

Organic electrode materials offer a versatile, sustainable approach for next-generation lithium-ion batteries but are limited by low working voltages and poor cycling stability. Here we report a solid-solvation-structure design strategy to improve both the voltage and stability of organic electro ...

Article GUID: 40759737

Author(s): Pollock D; Hasanoff S; McBride G; Kanukula R; Tricco AC; Khalil H; Campbell F; Jia RM; Alexander L; Peters M; Vieira AM; Aromataris E; Nunn J; Saran A; Evans C; Godfrey C; Pieper D; de Moraes ÉB; Biesty L; Colquhoun H; Devane D; Toomey E ...

Introduction: Scoping reviews, mapping reviews and evidence and gap maps (collectively known as 'big picture reviews') in health continue to gain popularity within the evidence ecosystem. These big-picture reviews are beneficial for policy-makers, guideline developers and researchers with ...

Article GUID: 40759523

Author(s): Usypchuk AA; Maes EJP; Lozzi M; Avramidis DK; Schoenbaum G; Esber GR; Gardner MPH; Iordanova MD;

The discovery that midbrain dopamine (DA) transients can be mapped onto reward prediction errors (RPEs), the critical signal that drives learning, is a landmark in neuroscience. Causal support for the RPE hypothesis comes from studies showing that stimulating DA neurons can drive learning under c ...

Article GUID: 40738112

Author(s): Peng H; Hao J; Lyu L; Wan S; An C;

Industrial fishing's harmful subsidies fuel both a fish stock crisis and rising greenhouse gas emissions, even as calls for a global ban by the World Trade Organization persist amid slow progress. This study employs the framework of climate policy stringency assessment to examine fisheries subsidy reform through a carbon pricing lens. Using emissions, ...

Article GUID: 40737555