Author(s): Zykaj E; Abboud C; Asadi P; Warsame S; Almousa H; Milev MP; Greco BM; López-Sánchez M; Bratkovic D; Kachroo AH; Pérez-Jurado LA; Sacher M; ...
Variants in membrane trafficking proteins are known to cause rare disorders with severe symptoms. The highly conserved transport protein particle (TRAPP) complexes are key membrane trafficking regu ...
Article GUID: 39273027
Author(s): Dandage R; Papkov M; Greco BM; Fishman D; Friesen H; Wang K; Styles E; Kraus O; Grys B; Boone C; Andrews B; Parts L; Kuzmin E; ...
Gene duplication is common across the tree of life, including yeast and humans, and contributes to genomic robustness. In this study, we examined changes in the subcellular localization and abundan ...
Article GUID: 38045359
Author(s): Abdullah M; Greco BM; Laurent JM; Garge RK; Boutz DR; Vandeloo M; Marcotte EM; Kachroo AH; ...
A major challenge to rationally building multi-gene processes in yeast arises due to the combinatorics of combining all of the individual edits into the same strain. Here, we present a precise and ...
Article GUID: 37323580
Author(s): Kachroo AH; Vandeloo M; Greco BM; Abdullah M;
For decades, budding yeast, a single-cellular eukaryote, has provided remarkable insights into human biology. Yeast and humans share several thousand genes despite morphological and cellular differences and over a billion years of separate evolution. These ...
Article GUID: 35661208
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