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Peripheral Arterial Disease in Nova Scotia: Increased Prevalence, Low Public Awareness, and Poor Edinburgh Claudication Questionnaire Sensitivity

Authors: MacLean EAFogarty EJPeterson BJXu SGiacomantonio NB


Affiliations

1 MD Candidate, Department of Medicine, Dalhousie University, Halifax, Nova Scotia, Canada.
2 Department of Science, Dalhousie University, Halifax, Nova Scotia, Canada.
3 Department of Nursing, University of Prince Edward Island, Charlottetown, Prince Edward Island, Canada.
4 Department of Arts and Social Sciences, Carleton University, Ottawa, Ontario, Canada.
5 Department of Fine Arts, Concordia University, Montreal, Quebec, Canada.
6 Department of Science, University of Toronto, Toronto, Ontario, Canada.
7 Department of Medicine, Memorial University, St. John's, Newfoundland, Canada.
8 Division of Cardiology, Department of Medicine, Dalhousie University, Halifax, Nova Scotia, Canada.

Description

Background: This study had the following 3 goals: (i) to assess the prevalence of peripheral arterial disease (PAD) in a Nova Scotian population; (ii) to evaluate the validity of the Edinburgh Claudication Questionnaire (ECQ) in a Nova Scotian context; and (iii) to evaluate Nova Scotian public knowledge about PAD.

Methods: Participants were recruited from 8 sites across Nova Scotia. In 2022, they were recruited at Heartland Tour (HLT) sites-a provincial health-promotion campaign. In 2023, they were recruited in communities coinciding with HLT sites (public [PUB]). Participants completed a demographics questionnaire, ECQ, and had an ankle-brachial index (ABI) measurement. An ABI of < 0.9 was considered positive for presence of PAD.

Results: A total of 417 participants were recruited, 263 from HLT, and 154 from PUB. A total of 398 participants had ABI scores resulting in a PAD prevalence of 2.81% (249 participants) in the HLT group, and 5.37% (149 participants) in the PUB group. A total of 394 participants had both ABI and ECQ scores, with a found sensitivity of 6.67% (confidence interval 0.17%-31.95%) and specificity of 97.63% (confidence interval 95.54%-98.91%). A total of 75% of participants (311 of 417) did not have prior knowledge of PAD.

Conclusions: The PAD prevalences in both cohorts were higher than anticipated, with the PUB cohort being more than double the national average. This finding raises the following question: should specific PAD primary and/or secondary prevention strategies be targeted within the province? Our study demonstrated that a public-awareness campaign would be highly impactful, owing to a low level of awareness of PAD within both cohorts, and that the ECQ was not an effective screening tool when used on the Nova Scotian population.


Links

PubMed: https://pubmed.ncbi.nlm.nih.gov/39525342/

DOI: 10.1016/j.cjco.2024.07.003