Author(s): Cigana B; Lapointe V; Majewski MB; Forgione P;
A library of 2,5-furan-based phenylene/thiophene oligomers were synthesized starting from 5-bromofurfural, a derivative of biomass-derived furfural. Varied electronic groups are coupled onto the furan motif, followed by the installation of a phenylene or th ...
Article GUID: 38808994
Author(s): Charoughchi S; Liu JT; Berteau-Rainville M; Hase H; Askari MS; Bhagat S; Forgione P; Salzmann I; ...
Molecular p-dopants designed to undergo electron transfer with organic semiconductors are typically planar molecules with high electron affinity. However, their planarity can promote the formation ...
Article GUID: 37220083
Author(s): Chacón-Huete F; Messina C; Cigana B; Forgione P;
This Review summarizes recent efforts to capitalize on 5-hydroxymethylfurfural (HMF) and related furans as emerging building blocks for the synthesis of fine chemicals and materials, with a focus on advanced applications within medicinal and polymer chemist ...
Article GUID: 35652539
Author(s): Hernandez R RA; Burchell-Reyes K; Braga APCA; Lopez JK; Forgione P;
Scalable, solvent-free synthesis of 3,5-isoxazoles under ball-milling conditions has been developed. The proposed methodology allows the synthesis of 3,5-isoxazoles in moderate to excellent yields from terminal alkynes and hydroxyimidoyl chlorides, using a ...
Article GUID: 35424611
Author(s): Jaunky DB; Larocque K; Husser MC; Liu JT; Forgione P; Piekny A;
We reveal the effects of a new microtubule-destabilizing compound in human cells. C75 has a core thienoisoquinoline scaffold with several functional groups amenable to modification. Previously we found that sub micromolar concentrations of C75 caused cytoto ...
Article GUID: 34880347
Author(s): Messina C; Ottenwaelder X; Forgione P;
Herein, we report a modular synthetic route to access tetra-arylated thiophene compounds with four different substituents with programmed chemical control provided by an ester activating/directing group. This method enables the functionalization of individu ...
Article GUID: 34506149
Author(s): Liu JT; Jaunky DB; Larocque K; Chen F; Mckibbon K; Sirouspour M; Taylor S; Shafeii A; Campbell D; Braga H; Piekny A; Forgione P; ...
Several derivatives of a series that share a thienoisoquinoline scaffold have demonstrated potent anti-cancer activity against cancer cell lines A549, HeLa, HCT-116 in the submicromolar concentrati ...
Article GUID: 34416378
Author(s): Chacón-Huete F, Lasso JD, Szavay P, Covone J, Forgione P
Biomass-derived commodity chemical 5-hydroxymethyl furfural is an underutilized C6-platform chemical derived from cellulose that is ideal to prepare next-generation value-added products. We have developed an efficient synthetic strategy to access 2,5-diaryl ...
Article GUID: 33253575
Author(s): Liu JT; Hase H; Taylor S; Salzmann I; Forgione P;
A library of symmetrical linear oligothiophene was prepared employing decarboxylative cross-coupling reaction as the key transformation. Thiophene potassium carboxylate salts were used as cross-coupling partners without the need of co-catalyst, base, or add ...
Article GUID: 31961982
Author(s): Liang Y, Manioudakis J, Macairan JR, Askari MS, Forgione P, Naccache R
ACS Omega. 2019 Sep 17;4(12):14955-14961 Authors: Liang Y, Manioudakis J, Macairan JR, Askari MS, Forgione P, Naccache R
Article GUID: 31552336
Author(s): Bastos Lda C, de Souza FR, Guimarães AP, Sirouspour M, Cuya Guizado TR, Forgione P, Ramalho TC, França TC
J Biomol Struct Dyn. 2016 Oct;34(10):2184-98 Authors: Bastos Lda C, de Souza FR, Guimarães AP, Sirouspour M, Cuya Guizado TR, Forgione P, Ramalho TC, França TC
Article GUID: 26494420
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