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Impact of a national dementia research consortium: The Canadian Consortium on Neurodegeneration in Aging (CCNA)

Author(s): Chertkow H; Phillips N; Rockwood K; Anderson N; Andrew MK; Bartha R; Beaudoin C; BĂ©langer N; Bellec P; Belleville S; Bergman H; Best S; Bethell J; Bherer L; Black S; Borrie M; Camicioli R; Carrier J; Cashman N; Chan S; Crowshoe L; Cuello ...

The Canadian Consortium on Neurodegeneration in Aging (CCNA) was created by the Canadian federal government through its health research funding agency, the Canadian Institutes for Health Research (CIHR), in 2014, as a response to the G7 initiative to fight dementia. Two five-year funding cycles ( ...

Article GUID: 39636028


Web-based processing of physiological noise in fMRI: addition of the PhysIO toolbox to CBRAIN

Author(s): Valevicius D; Beck N; Kasper L; Boroday S; Bayer J; Rioux P; Caron B; Adalat R; Evans AC; Khalili-Mahani N;

Neuroimaging research requires sophisticated tools for analyzing complex data, but efficiently leveraging these tools can be a major challenge, especially on large datasets. CBRAIN is a web-based platform designed to simplify the use and accessibility of neuroimaging research tools for large-scal ...

Article GUID: 37841811


Data and Tools Integration in the Canadian Open Neuroscience Platform

Author(s): Poline JB; Das S; Glatard T; Madjar C; Dickie EW; Lecours X; Beaudry T; Beck N; Behan B; Brown ST; Bujold D; Beauvais M; Caron B; Czech C; Dharsee M; Dugré M; Evans K; Gee T; Ippoliti G; Kiar G; Knoppers BM; Kuehn T; Le D; Lo D; Mazaheri ...

We present the Canadian Open Neuroscience Platform (CONP) portal to answer the research community's need for flexible data sharing resources and provide advanced tools for search and processing infrastructure capacity. This portal differs from previous data sharing projects as it integrates d ...

Article GUID: 37024500


Numerical uncertainty in analytical pipelines lead to impactful variability in brain networks

Author(s): Kiar G; Chatelain Y; de Oliveira Castro P; Petit E; Rokem A; Varoquaux G; Misic B; Evans AC; Glatard T;

The analysis of brain-imaging data requires complex processing pipelines to support findings on brain function or pathologies. Recent work has shown that variability in analytical decisions, small amounts of noise, or computational environments can lead to substantial differences in the results, ...

Article GUID: 34724000


The BigBrainWarp toolbox for integration of BigBrain 3D histology with multimodal neuroimaging

Author(s): Paquola C; Royer J; Lewis LB; Lepage C; Glatard T; Wagstyl K; DeKraker J; Toussaint PJ; Valk SL; Collins DL; Khan A; Amunts K; Evans AC; Dickscheid T; Bernhardt BC;

Neuroimaging stands to benefit from emerging ultrahigh-resolution 3D histological atlases of the human brain; the first of which is 'BigBrain'. Here, we review recent methodological advances for the integration of BigBrain with multi-modal neuroimaging and introduce a toolbox, 'BigBra ...

Article GUID: 34431476


A Simulation Toolkit for Testing the Sensitivity and Accuracy of Corticometry Pipelines

Author(s): OmidYeganeh M; Khalili-Mahani N; Bermudez P; Ross A; Lepage C; Vincent RD; Jeon S; Lewis LB; Das S; Zijdenbos AP; Rioux P; Adalat R; Van Eede MC; Evans AC;

In recent years, the replicability of neuroimaging findings has become an important concern to the research community. Neuroimaging pipelines consist of myriad numerical procedures, which can have a cumulative effect on the accuracy of findings. To address this problem, we propose a method for si ...

Article GUID: 34381348


File-based localization of numerical perturbations in data analysis pipelines.

Author(s): Salari A, Kiar G, Lewis L, Evans AC, Glatard T

BACKGROUND: Data analysis pipelines are known to be affected by computational conditions, presumably owing to the creation and propagation of numerical errors. While this process could play a major role in the current reproducibility crisis, the precise causes of such instabilities and the path along which they propagate in pipelines are unclear. METHOD: ...

Article GUID: 33269388


Comparing perturbation models for evaluating stability of neuroimaging pipelines.

Author(s): Kiar G, de Oliveira Castro P, Rioux P, Petit E, Brown ST, Evans AC, Glatard T

With an increase in awareness regarding a troubling lack of reproducibility in analytical software tools, the degree of validity in scientific derivatives and their downstream results has become unclear. The nature of reproducibility issues may vary across domains, tools, data sets, and computational infrastructures, but numerical instabilities are though ...

Article GUID: 32831546


Cyberinfrastructure for Open Science at the Montreal Neurological Institute.

Author(s): Das S, Glatard T, Rogers C, Saigle J, Paiva S, MacIntyre L, Safi-Harab M, Rousseau ME, Stirling J, Khalili-Mahani N, MacFarlane D, Kostopoulos P, Rioux P, Madjar C, Lecours-Boucher X, Vanamala S, Adalat R, Mohaddes Z, Fonov VS, Milot S, ...

Front Neuroinform. 2016;10:53 Authors: Das S, Glatard T, Rogers C, Saigle J, Paiva S, MacIntyre L, Safi-Harab M, Rousseau ME, Stirling J, Khalili-Mahani N, MacFarlane D, Kostopoulos P, Rioux P, Madjar C, Lecours-Boucher X, Vanamala S, Adalat R, Mohaddes Z, Fonov VS, Milot S, Leppert I, Degroot C ...

Article GUID: 28111547


Best practices in data analysis and sharing in neuroimaging using MRI.

Author(s): Nichols TE, Das S, Eickhoff SB, Evans AC, Glatard T, Hanke M, Kriegeskorte N, Milham MP, Poldrack RA, Poline JB, Proal E, Thirion B, Van Essen DC, White T, Yeo BT

Nat Neurosci. 2017 Feb 23;20(3):299-303 Authors: Nichols TE, Das S, Eickhoff SB, Evans AC, Glatard T, Hanke M, Kriegeskorte N, Milham MP, Poldrack RA, Poline JB, Proal E, Thirion B, Van Essen DC, White T, Yeo BT

Article GUID: 28230846


Boutiques: a flexible framework to integrate command-line applications in computing platforms.

Author(s): Glatard T, Kiar G, Aumentado-Armstrong T, Beck N, Bellec P, Bernard R, Bonnet A, Brown ST, Camarasu-Pop S, Cervenansky F, Das S, Ferreira da Silva R, Flandin G, Girard P, Gorgolewski KJ, Guttmann CRG, Hayot-Sasson V, Quirion PO, Rioux P, ...

Gigascience. 2018 05 01;7(5): Authors: Glatard T, Kiar G, Aumentado-Armstrong T, Beck N, Bellec P, Bernard R, Bonnet A, Brown ST, Camarasu-Pop S, Cervenansky F, Das S, Ferreira da Silva R, Flandin G, Girard P, Gorgolewski KJ, Guttmann CRG, Hayot-Sasson V, Quirion PO, Rioux P, Rousseau MÉ, E ...

Article GUID: 29718199


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