Author(s): Jenner AL; Aogo RA; Alfonso S; Crowe V; Smith AP; Morel PA; Davis CL; Smith AM; Craig M;

To understand the diversity of immune responses to SARS-CoV-2 and distinguish features that predispose individuals to severe COVID-19, we developed a mechanistic, within-host mathematical model and virtual patient cohort. Our results indicate that virtual patients with low production rates of infected cell derived IFN subsequently experienced highly infla ...

Article GUID: 33442689

Author(s): Jenner AL; Aogo RA; Alfonso S; Crowe V; Deng X; Smith AP; Morel PA; Davis CL; Smith AM; Craig M;

To understand the diversity of immune responses to SARS-CoV-2 and distinguish features that predispose individuals to severe COVID-19, we developed a mechanistic, within-host mathematical model and virtual patient cohort. Our results suggest that virtual patients with low production rates of infe ...

Article GUID: 34260666