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Engineering Yeast for De Novo Synthesis of the Insect Repellent Nepetalactone

Author(s): Davies ME; Tsyplenkov D; Martin VJJ;

While nepetalactone, the active ingredient in catnip, is a potent insect repellent, its low in planta accumulation limits its commercial viability as an alternative repellent. Here we describe for the first time de novo nepetalactone synthesis in Saccharomyces cerevisiae, enabling sustainable and scalable production. Nepetalactone production required intr ...

Article GUID: 34748704


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