Author(s): Ozturk TN; Culham DE; Tempelhagen L; Wood JM; Lamoureux G;

Osmosensing transporter ProP detects the increase in cytoplasmic cation concentration associated with osmotically induced cell dehydration and mediates osmolyte uptake into bacteria. ProP is a 12-transmembrane helix protein with an a-helical, cytoplasmic C-terminal domain (CTD) linked to transmembrane helix XII (TM XII). It has been proposed that the CTD ...

Article GUID: 32838524

Author(s): Culham DE; Marom D; Boutin R; Garner J; Ozturk TN; Sahtout N; Tempelhagen L; Lamoureux G; Wood JM;

ProP is a member of the major facilitator superfamily, a proton-osmolyte symporter, and an osmosensing transporter. ProP proteins share extended cytoplasmic carboxyl terminal domains (CTDs) implicated in osmosensing. The CTDs of the best characterized, group A ProP orthologs, terminate in sequenc ...

Article GUID: 30448037