Author(s): Jenner AL; Aogo RA; Alfonso S; Crowe V; Smith AP; Morel PA; Davis CL; Smith AM; Craig M;

To understand the diversity of immune responses to SARS-CoV-2 and distinguish features that predispose individuals to severe COVID-19, we developed a mechanistic, within-host mathematical model and virtual patient cohort. Our results indicate that virtual patients with low production rates of infected cell derived IFN subsequently experienced highly infla ...

Article GUID: 33442689

Author(s): Uthamacumaran A; Craig M;

Glioblastoma is a complex disease that is difficult to treat. Network and data science offer alternative approaches to classical bioinformatics pipelines to study gene expression patterns from single-cell datasets, helping to distinguish genes associated with the control of differentiation and aggression. To identify the key molecular regulators of the ne ...

Article GUID: 35479408

Author(s): Jenner AL; Aogo RA; Alfonso S; Crowe V; Deng X; Smith AP; Morel PA; Davis CL; Smith AM; Craig M;

To understand the diversity of immune responses to SARS-CoV-2 and distinguish features that predispose individuals to severe COVID-19, we developed a mechanistic, within-host mathematical model and virtual patient cohort. Our results suggest that virtual patients with low production rates of infe ...

Article GUID: 34260666