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Iron Deposition and Distribution Across the Hippocampus Is Associated with Pattern Separation and Pattern Completion in Older Adults at Risk for Alzheimer's Disease

Author(s): Zhou J; Wearn A; Huck J; Hughes C; Baracchini G; Tremblay-Mercier J; Poirier J; Villeneuve S; Tardif CL; Chakravarty MM; Daugherty AM; Gauthier CJ; Turner GR; Spreng RN;

Elevated iron deposition in the brain has been observed in older adult humans and persons with Alzheimer's disease (AD), and has been associated with lower cognitive performance. We investigated the impact of iron deposition, and its topographical distribution across hippocampal subfields and ...

Article GUID: 38388425


Mapping pontocerebellar connectivity with diffusion MRI

Author(s): Rousseau PN; Chakravarty MM; Steele CJ;

The cerebellum's involvement in cognitive, affective and motor functions is mediated by connections to different regions of the cerebral cortex. A distinctive feature of cortico-cerebellar loops that has been demonstrated in the animal work is a topographic organization that is preserved across its corticopontine, pontocerebellar, and cerebello-thalmo ...

Article GUID: 36252913


Early musical training shapes cortico-cerebellar structural covariation

Author(s): Shenker JJ; Steele CJ; Chakravarty MM; Zatorre RJ; Penhune VB;

Adult abilities in complex cognitive domains such as music appear to depend critically on the age at which training or experience begins, and relevant experience has greater long-term effects during periods of peak maturational change. Previous work has shown that early trained musicians (ET; < age 7) out-perform later-trained musicians (LT; > age 7 ...

Article GUID: 34657166


Investigating microstructural variation in the human hippocampus using non-negative matrix factorization.

Author(s): Patel R, Steele CJ, Chen A, Patel S, Devenyi GA, Germann J, Tardif CL, Chakravarty MM

Neuroimage. 2019 Nov 09;:116348 Authors: Patel R, Steele CJ, Chen A, Patel S, Devenyi GA, Germann J, Tardif CL, Chakravarty MM

Article GUID: 31715254


Regional cerebellar volumes are related to early musical training and finger tapping performance.

Author(s): Baer LH, Park MT, Bailey JA, Chakravarty MM, Li KZ, Penhune VB

Neuroimage. 2015 Apr 01;109:130-9 Authors: Baer LH, Park MT, Bailey JA, Chakravarty MM, Li KZ, Penhune VB

Article GUID: 25583606


A dataset of multi-contrast population-averaged brain MRI atlases of a Parkinson׳s disease cohort.

Author(s): Xiao Y, Fonov V, Chakravarty MM, Beriault S, Al Subaie F, Sadikot A, Pike GB, Bertrand G, Collins DL

Data Brief. 2017 Jun;12:370-379 Authors: Xiao Y, Fonov V, Chakravarty MM, Beriault S, Al Subaie F, Sadikot A, Pike GB, Bertrand G, Collins DL

Article GUID: 28491942


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