Author(s): Bietar K; Chu S; Mandl G; Zhang E; Chabaytah N; Sabelli R; Capobianco JA; Stochaj U;

Lanthanide-doped upconverting nanoparticles (UCNPs) are ideal candidates for use in biomedicine. The interaction of nanomaterials with biological systems determines whether they are suitable for use in living cells. In-depth knowledge of the nano-bio interactions is therefore a pre-requisite for the development of biomedical applications. The current stud ...

Article GUID: 38495986

Author(s): Mena-Giraldo P; Kaur M; Maurizio SL; Mandl GA; Capobianco JA;

External stimuli can trigger changes in temperature, concentration, and momentum between micromotors and the medium, causing their propulsion and enabling them to perform different tasks with improved kinetic efficiencies. Light-activated micromotors are attractive systems that achieve improved motion and have the potential for high spatiotemporal control ...

Article GUID: 38197400

Author(s): Kaur M; Maurizio SL; Mandl GA; Capobianco JA;

Dye sensitization is a promising approach to enhance the luminescence of lanthanide-doped upconverting nanoparticles. However, the poor photostability of near-infrared dyes hampers their use in practical applications. To address this, commercial IR820 was modified for improved photostability and covalently bonded to amine-functionalized silica-coated LnUC ...

Article GUID: 37552506

Author(s): Tessitore G; Mandl GA; Maurizio SL; Kaur M; Capobianco JA;

Our society is indebted to the numerous inventors and scientists who helped bring about the incredible technological advances in modern society that we all take for granted. The importance of knowing the history of these inventions is often underestimated, although our reliance on technology is escalating. Lanthanide luminescence has paved the way for man ...

Article GUID: 37323462

Author(s): Mandl GA; Vettier F; Tessitore G; Maurizio SL; Bietar K; Stochaj U; Capobianco JA;

Glioblastoma multiforme is an aggressive type of brain cancer with high recurrence rates due to the presence of radioresistant cells remaining after tumor resection. Here, we report the development of an X-ray-mediated photodynamic therapy (X-PDT) system using NaLuF4:25% Pr3+ radioluminescent nanoparticles in conjunction with protoporphyrin IX (PPIX), an ...

Article GUID: 37267436

Author(s): Sun G; Xie Y; Wang Y; Mandl GA; Maurizio SL; Zhang H; Ottenwaelder X; Capobianco JA; Sun L;

Lanthanide upconversion luminescence in nanoparticles has prompted continuous breakthroughs in information storage, temperature sensing, and biomedical applications, among others. Achieving upconversion luminescence at the molecular scale is still a critical challenge in modern chemistry. In this ...

Article GUID: 37040148

Author(s): Aminzare M; Jiang J; Mandl GA; Mahshid S; Capobianco JA; Dorval Courchesne NM;

Halide perovskite nanocrystals (HPNCs) have emerged at the forefront of nanomaterials research over the past two decades. The physicochemical and optoelectronic properties of these inorganic semiconductor nanoparticles can be modulated through the introduction of various ligands. The use of biomolecules as ligands has been demonstrated to improve the stab ...

Article GUID: 36722934

Author(s): Xie Y; Sun G; Mandl GA; Maurizio SL; Chen J; Capobianco JA; Sun L;

Lanthanide-doped metal-organic frameworks (Ln-MOFs) have versatile luminescence properties, however it is challenging to achieve lanthanide-based upconversion luminescence in these materials. Here, 1,3,5-benzenetricarboxylic acid (BTC) and trivalent Yb3+ ions were used to generate crystalline Yb-BTC MOF 1D-microrods with upconversion luminescence under ne ...

Article GUID: 36437239

Author(s): Nsubuga A; Mandl GA; Capobianco JA;

Radioluminescent nanomaterials have garnered significant attention in the past decade due to their potential to perform X-ray mediated photodynamic therapy (X-PDT). Many of these materials are assumed to produce singlet oxygen based on a single assay. Herein we demonstrate that multiple assays are required to confidently determine whether singlet oxygen o ...

Article GUID: 36132856

Author(s): Kaur M; Mandl GA; Maurizio SL; Tessitore G; Capobianco JA;

Dye sensitization is a promising route to enhance luminescence from lanthanide-doped upconverting nanoparticles (LnUCNPs) by improving the photon harvesting capability of LnUCNPs through the use of dye molecules, characterized by higher absorption coefficients. The literature does not fully address the poor photostability of NIR dyes, hindering solution-b ...

Article GUID: 36132705

Author(s): Londoño-Berrío M; Pérez-Buitrago S; Ortiz-Trujillo IC; Hoyos-Palacio LM; Orozco LY; López L; Zárate-Triviño DG; Capobianco JA; Mena-Giraldo P;

Drug nanoencapsulation increases the availability, pharmacokinetics, and concentration efficiency for therapeutic regimes. Azobenzene light-responsive molecules experience a hydrophobicity change from a polar to an apolar tendency by trans-cis photoisomerization upon UV irradiation. Polymeric pho ...

Article GUID: 35956634