Author(s): Zhang C; Calderin JD; Hurst LR; Gokbayrak ZD; Hrabak MR; Balutowski A; Rivera-Kohr DA; Kazmirchuk TDD; Brett CL; Fratti RA;

Sphingolipids are essential in membrane trafficking and cellular homeostasis. Here, we show that sphingolipids containing very long-chain fatty acids (VLCFAs) promote homotypic vacuolar fusion in Saccharomyces cerevisiae. The elongase Elo3 adds the last two carbons to VLCFAs that are incorporated ...

Article GUID: 39307308