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Ghrelin receptor signalling is not required for glucocorticoid-induced obesity in female mice

Author(s): Silver Z; Abbott-Tate S; Hyland L; Sherratt F; Woodside B; Abizaid A;

Chronic exposure to high circulating glucocorticoid or ghrelin concentrations increases food intake, weight gain and adiposity, suggesting that ghrelin could contribute to the metabolic effects of chronic glucocorticoids. In male mice, however, blocking ghrelin receptor (GHSR) signalling increased the weight gain and adiposity induced by chronic corticost ...

Article GUID: 34060474


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