Author(s): Borges C; Darecka A; Mainville-Berthiaume A; Ah-Yen E; Darvishmolla M; Courtemanche R; Shalev U;

Abstinence from drug use is often the result of the associated negative consequences. However, relapse occurs in a large proportion of abstinent users, and the underlying brain mechanisms are not clear. An arguably relevant brain area is the posterior paraventricular nucleus of the thalamus (pPVT ...

Article GUID: 41506524

Author(s): Borges C; Inigo F; Quteishat N; Charles J; Ah-Yen E; U S;

Rational: Stress is a major trigger for drug relapse in humans and animal models, even after prolonged abstinence. However, animal models for stress-induced relapse were criticized for the lack of predictive and face validity.
Objectives: Here we investigated the effect of acute food deprivation stress in a novel str ...

Article GUID: 35951079