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Leveraging Personal Technologies in the Treatment of Schizophrenia Spectrum Disorders: Scoping Review

Author(s): D' Arcey J; Torous J; Asuncion TR; Tackaberry-Giddens L; Zahid A; Ishak M; Foussias G; Kidd S; ...

Background: Digital mental health is a rapidly growing field with an increasing evidence base due to its potential scalability and impacts on access to mental health care. Further, within underfund ...

Article GUID: 39348196


Microfluidic Wound-Healing Assay for Comparative Study on Fluid Dynamic, Chemical and Mechanical Wounding on Microglia BV2 Migration

Author(s): Yazdanpanah Moghadam E; Sonenberg N; Packirisamy M;

Microglial cells, or brain immune cells, are highly dynamic and continuously migrate in pathophysiological conditions. Their adhesion, as a physical characteristic, plays a key role in migration. In this study, we presented a microfluidic chip combination o ...

Article GUID: 39203655


"How do we do that?" An analysis of TikToks by lesbians over age 30 representing sexual identity, lived experience over time, and solidarity

Author(s): Jamet-Lange H; Duguay S;

Lesbians have long turned to digital media and technologies for information, support, and to self-represent sexual identity in ways that have the capacity for building communities and gathering publics and counterpublics. TikTok is a short video platform po ...

Article GUID: 38907626


Discovery and preclinical development of a therapeutically active nanobody-based chimeric antigen receptor targeting human CD22

Author(s): McComb S; Arbabi-Ghahroudi M; Hay KA; Keller BA; Faulkes S; Rutherford M; Nguyen T; Shepherd A; Wu C; Marcil A; Aubry A; Hussack G; Pinto DM ...

Chimeric antigen receptor (CAR) T cell therapies targeting B cell-restricted antigens CD19, CD20, or CD22 can produce potent clinical responses for some B cell malignancies, but relapse remains com ...

Article GUID: 38596311


Brain PET Imaging in Small Animals: Tracer Formulation, Data Acquisition, Image Reconstruction, and Data Analysis

Author(s): Bdair H; Kang MS; Ottoy J; Aliaga A; Kunach P; Singleton TA; Blinder S; Soucy JP; Leyton M; Rosa-Neto P; Kostikov A; ...

Positron emission tomography (PET) is a noninvasive functional imaging modality that involves in vivo detection of spatiotemporal changes in the binding of radioactive pharmaceuticals (a.k.a. PET t ...

Article GUID: 38006502


The impact of COVID-19 on the lives of Canadians with and without non-communicable chronic diseases: results from the iCARE Study

Author(s): Deslauriers F; Gosselin-Boucher V; Léger C; Vieira AM; Bacon SL; Lavoie KL;

Background: The COVID-19 pandemic and its prevention policies have taken a toll on Canadians, and certain subgroups may have been disproportionately affected, including those with non-communicable diseases (NCDs; e.g., heart and lung disease) due to their r ...

Article GUID: 37884921


Assessing pragmatics in early childhood with the Language Use Inventory across seven languages

Author(s): Pesco D; O' Neill DK;

The Language Use Inventory (LUI) is a parent-report measure of the pragmatic functions of young children's language, standardized and norm-referenced in English (Canada) for children aged 18-47 months. The unique focus of the LUI, along with its appeal ...

Article GUID: 37408974


Impact Behaviour of Steel-Fibre-Reinforced Alkali-Activated Slag Concrete Exposed to Elevated Temperatures

Author(s): Abubakr A; Soliman A;

Concrete protective structures are mainly meant to withstand impact loads. However, fire events weaken concrete and reduce its impact resistance. This study investigated the impact behaviour of steel-fibre-reinforced alkali-activated slag (AAS) concrete bef ...

Article GUID: 37297228


How to present work productivity loss results from clinical trials for patients and caregivers? A mixed methods approach

Author(s): L' Heureux J; McTaggart-Cowan H; Johns G; Chen L; Steiner T; Tocher P; Sun H; Zhang W; ...

Objectives: From the perspectives of patients and caregivers, the objectives were: identifying which result presentations, describing work productivity loss (WPL) outcomes, are most understandable; ...

Article GUID: 37276772


Prospects of Novel and Repurposed Immunomodulatory Drugs against Acute Respiratory Distress Syndrome (ARDS) Associated with COVID-19 Disease

Author(s): Nayak SS; Naidu A; Sudhakaran SL; Vino S; Selvaraj G;

Acute respiratory distress syndrome (ARDS) is intricately linked with SARS-CoV-2-associated disease severity and mortality, especially in patients with co-morbidities. Lung tissue injury caused as a consequence of ARDS leads to fluid build-up in the alveola ...

Article GUID: 37109050


The association between information and communication technologies, loneliness and social connectedness: A scoping review

Author(s): Petersen B; Khalili-Mahani N; Murphy C; Sawchuk K; Phillips N; Li KZH; Hebblethwaite S;

Older adults are at a higher risk of loneliness, compared to other demographics. The use of Internet Communication and Technologies (ICTs) among older adults is steadily increasing and given ICTs provide a means of enhancing social connectedness suggests th ...

Article GUID: 37034933


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