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Connected speech profiles in mild cognitive impairment reflect global cognition

Author(s): Pellerin S; Houzé B; Bedetti C; Phillips N; Brambati SM;

BackgroundMild cognitive impairment (MCI), a prodromal stage of Alzheimer's disease (AD) for many individuals, is accompanied by widespread connected speech (CS) changes (e.g., shorter CS samples, mention of fewer semantic content units, lower syntactic complexity). Nevertheless, findings on CS in MCI are heterogeneous. This heterogeneity, combined wi ...

Article GUID: 40232260


Disruptive effects of d-amphetamine on conditioned sexual inhibition in the male rat

Author(s): Germé K; Persad D; Petit-Robinson J; Amir S; Pfaus JG;

Rationale: Male rats trained to associate a neutral odor (almond) with nonreceptive females during their initial sexual experiences develop a conditioned sexual inhibition (CSI) toward the female bearing the olfactory cue when given a choice in a final copulatory preference test between two receptive females (one unscented and one scented) in an open fiel ...

Article GUID: 40232387


An Effective and Fast Model for Characterization of Cardiac Arrhythmia and Congestive Heart Failure

Author(s): Lahmiri S; Bekiros S;

Background/Objectives: Cardiac arrhythmia (ARR) and congestive heart failure (CHF) are heart diseases that can cause dysfunction of other body organs and possibly death. This paper describes a fast and accurate detection system to distinguish between ARR and normal sinus (NS), and between CHF and NS. Methods: the proposed automatic detection system uses t ...

Article GUID: 40218199


Clustering and Interpretability of Residential Electricity Demand Profiles

Author(s): Kallel S; Amayri M; Bouguila N;

Efficient energy management relies on uncovering meaningful consumption patterns from large-scale electricity load demand profiles. With the widespread adoption of sensor technologies such as smart meters and IoT-based monitoring systems, granular and real-time electricity usage data have become available, enabling deeper insights into consumption behavio ...

Article GUID: 40218540


Rubber Fatigue Revisited: A State-of-the-Art Review Expanding on Prior Works by Tee, Mars and Fatemi

Author(s): Wang X; Sedaghati R; Rakheja S; Shangguan W;

Rubber materials can endure substantial deformation while avoiding permanent damage or rupture, making them highly suitable for applications in the automotive industry and other sectors, particularly for noise and vibration reduction. However, rubber experiences degradation over time as defects or cracks appear and propagate under fluctuating loads. There ...

Article GUID: 40219307


Hyperbranched Polyethylene Ionomers Containing Quaternary Ammonium Ions and Their Functionalization of Nanomaterials

Author(s): Ye Z; Rahmatinejad J; Raisi B; Dai P;

Ionomers containing a small number of ionic side groups are a unique class of polymers with some valuable properties and distinct applications. To date, commercially important ionomers are exclusively anionomers that contain covalently bonded anions and are synthesized commonly by radical polymerization. The catalytic synthesis of polyethylene-based catio ...

Article GUID: 40214570


Parallel boosting neural network with mutual information for day-ahead solar irradiance forecasting

Author(s): Ahmed U; Mahmood A; Khan AR; Kuhlmann L; Alimgeer KS; Razzaq S; Aziz I; Hammad A;

The transition to sustainable energy has become imperative due to the depletion of fossil fuels. Solar energy presents a viable alternative owing to its abundance and environmental benefits. However, the intermittent nature of solar energy requires accurate forecasting of solar irradiance (SI) for reliable operation of photovoltaics (PVs) integrated syste ...

Article GUID: 40185800


Addressing vaccine hesitancy: A systematic review comparing the efficacy of motivational versus educational interventions on vaccination uptake

Author(s): Labbé S; Bacon SL; Wu N; Ribeiro PAB; Boucher VG; Stojanovic J; Voisard B; Deslauriers F; Tremblay N; Hébert-Auger L; Lavoie KL;

Traditional approaches to increase vaccination rely upon educating patients about vaccines. However, research shows that "knowing" vaccines are important is often insufficient: patients need to believe that getting vaccinated is important. Evidence-based motivational approaches, such as ...

Article GUID: 40167044


Large language models deconstruct the clinical intuition behind diagnosing autism

Author(s): Stanley J; Rabot E; Reddy S; Belilovsky E; Mottron L; Bzdok D;

Efforts to use genome-wide assays or brain scans to diagnose autism have seen diminishing returns. Yet the clinical intuition of healthcare professionals, based on longstanding first-hand experience, remains the gold standard for diagnosis of autism. We leveraged deep learning to deconstruct and interrogate the logic of expert clinician intuition from cli ...

Article GUID: 40147442


Integrating past experiences

Author(s): Leir TMW; Gardner MPH;

New results help address a longstanding debate regarding which learning strategies allow animals to anticipate negative events based on past associations between sensory stimuli.

Article GUID: 40146623


Mirtazapine for chronic insomnia in older adults: a randomised double-blind placebo-controlled trial-the MIRAGE study

Author(s): Nguyen PV; Dang-Vu TT; Forest G; Desjardins S; Forget MF; Vu TT; Nguyen QD; Kouassi E; Desmarais P;

Background: Mirtazapine promotes sleep by blocking serotonin and histaminergic receptors and is often used off-label to treat chronic insomnia. However, its efficacy remains to be demonstrated in a clinical trial. The MIRAGE study aims to determine the efficacy and safety of mirtazapine in older ...

Article GUID: 40135470


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