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Microglial senescence in neurodegeneration: Insights, implications, and therapeutic opportunities

Author(s): Samuel Olajide T; Oyerinde TO; Omotosho OI; Okeowo OM; Olajide OJ; Ijomone OM;

The existing literature on neurodegenerative diseases (NDDs) reveals a common pathological feature: the accumulation of misfolded proteins. However, the heterogeneity in disease onset mechanisms and the specific brain regions affected complicates the unders ...

Article GUID: 39364217


Challenges and Approaches in the Study of Neural Entrainment

Author(s): Duecker K; Doelling KB; Breska A; Coffey EBJ; Sivarao DV; Zoefel B;

When exposed to rhythmic stimulation, the human brain displays rhythmic activity across sensory modalities and regions. Given the ubiquity of this phenomenon, how sensory rhythms are transformed into neural rhythms remains surprisingly inconclusive. An infl ...

Article GUID: 39358026


The temporal sequence and reciprocal relationships of frailty, social isolation and loneliness in older adults across 21 years

Author(s): Mehrabi F; Pomeroy ML; Cudjoe TKM; Jenkins E; Dent E; Hoogendijk EO;

Background: It is unclear whether social isolation and loneliness may precede frailty status or whether frailty may precipitate social isolation and loneliness. We investigated the reciprocal and temporal sequence of social isolation, loneliness, and frailt ...

Article GUID: 39360435


Reduction of Cr(VI) by Bacillus toyonensis LBA36 and its effect on radish seedlings under Cr(VI) stress

Author(s): Tan A; Wang H; Zhang H; Zhang L; Yao H; Chen Z;

Chromium, being among the most toxic heavy metals, continues to demand immediate attention in the remediation of Cr-contaminated environments. In this study, a strain of LBA36 (Bacillus toyonensis) was isolated from heavy metal contaminated soil in Luanchua ...

Article GUID: 39346031


Leveraging Personal Technologies in the Treatment of Schizophrenia Spectrum Disorders: Scoping Review

Author(s): D' Arcey J; Torous J; Asuncion TR; Tackaberry-Giddens L; Zahid A; Ishak M; Foussias G; Kidd S; ...

Background: Digital mental health is a rapidly growing field with an increasing evidence base due to its potential scalability and impacts on access to mental health care. Further, within underfund ...

Article GUID: 39348196


Comprehensive Analysis of Age- and Sex-Related Expression of the Chaperone Protein Sigma-1R in the Mouse Brain

Author(s): Tarmoun K; Lachance V; Le Corvec V; BĂ©langer SM; Beaucaire G; Kourrich S;

Sigma-1R (S1R) is a ubiquitously distributed protein highly expressed in the brain and liver. It acts as a ligand-inducible chaperone protein localized at the endoplasmic reticulum. S1R participates in several signaling pathways that oversee diverse cellula ...

Article GUID: 39335377


Neuroinflammation and oxidative redox imbalance drive memory dysfunction in adolescent rats prenatally exposed to Datura Stramonium

Author(s): Bamisi O; Oluwalabani AO; Arogundade TT; Olajide OJ;

Although there have been reports indicating that Datura Stramonium (D. stramonium) may induce anticholinergic and neuropsychiatry effects, the compound is still being used for recreational and medicinal purposes while ingestion during pregnancy has been doc ...

Article GUID: 39303770


Prototype Facial Response to Cute Stimuli: Expression and Recognition

Author(s): O' Neil MJ; Danvers AF; Hu JI; Shiota MN;

Cute, kindchenschema stimuli can evoke a suite of cognitive, physiological, and behavioral tendencies thought to promote caregiving. This research investigated facial expression elements associated with this response to cuteness and assessed the recognizabi ...

Article GUID: 39282978


SpeechBrain-MOABB: An open-source Python library for benchmarking deep neural networks applied to EEG signals

Author(s): Borra D; Paissan F; Ravanelli M;

Deep learning has revolutionized EEG decoding, showcasing its ability to outperform traditional machine learning models. However, unlike other fields, EEG decoding lacks comprehensive open-source libraries dedicated to neural networks. Existing tools (MOABB ...

Article GUID: 39265481


Exploring the glycoprotein washing fluid-assisted cleanup for the restoration of oil-contaminated shorelines with environmental integrity

Author(s): Sui J; Yue R; Bi H; Fu H; Yang A; Wang M; An C;

Spilled oil in ocean can spread to the shoreline and cause long-term impacts on the shoreline's ecological environment. Therefore, removing oil accumulated on shorelines is crucial. This study proposed an innovative ovalbumin (OVA) fluid-assisted method ...

Article GUID: 39260515


Developing endophytic Penicillium oxalicum as a source of lignocellulolytic enzymes for enhanced hydrolysis of biorefinery relevant pretreated rice straw

Author(s): Sharma G; Kaur B; Raheja Y; Kaur A; Singh V; Basotra N; Di Falco M; Tsang A; Chadha BS;

Endophytic fungi, as plant symbionts, produce an elaborate array of enzymes for efficient disintegration of lignocellulosic biomass into constituent monomeric sugars, making them novel source of lignocellulolytic CAZymes with immense potential in future bio ...

Article GUID: 39249151


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