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Beyond the Illusion of Controlled Environments: How to Embrace Ecological Pertinence in Research?

Author(s): Cassandre Vielle

Through the lens of preclinical research on substance use disorders (SUD), I propose a reflection aimed at re-evaluating animal models in neuroscience, with a focus on ecological relevance. While rodent models have provided valuable insights into the neurobiology of SUD, the field currently faces a validation crisis, with findings often failing to transla ...

Article GUID: 39777969


Psychosocial Function in Mild Cognitive Impairment: Social Participation is Associated With Cognitive Performance in Multiple Domains

Author(s): Rehan S; Phillips NA;

Psychosocial function is associated with cognitive performance cross-sectionally and cognitive decline over time. Using data from the COMPASS-ND study, we examined associations between psychosocial and cognitive function in 126 individuals with mild cognitive impairment, an at-risk group for Alzheimer's disease (AD). Psychosocial function was measured ...

Article GUID: 39773214


Long-lasting antimicrobial effect of multipurpose ZnO nanoparticle-loaded dental resins enhanced by blue light photodynamic therapy

Author(s): Leite ML; Comeau P; Zaghwan A; Shen Y; Manso AP;

Objectives: This study aimed to assess the potential of experimental dental resins containing ZnO nanoparticles (ZnO-NPs) for antimicrobial photodynamic therapy (aPDT) as a functional tool for the modulation of cariogenic biofilm in long-term. Methods: Minimum inhibitory and bactericidal concentrations (MIC/MBC) of ZnO-NPs against Streptococcus mutans we ...

Article GUID: 39765362


Semantically-Enhanced Feature Extraction with CLIP and Transformer Networks for Driver Fatigue Detection

Author(s): Gao Z; Chen X; Xu J; Yu R; Zhang H; Yang J;

Drowsy driving is a leading cause of commercial vehicle traffic crashes. The trend is to train fatigue detection models using deep neural networks on driver video data, but challenges remain in coarse and incomplete high-level feature extraction and network architecture optimization. This paper pioneers the use of the CLIP (Contrastive Language-Image Pre- ...

Article GUID: 39771685


Translating Evidence-Based Self-Management Interventions Using a Stepped-Care Approach for Patients With Cancer and Their Caregivers: A Pilot Sequential Multiple Assignment Randomized Trial Design

Author(s): Lambert S; Moodie EEM; McCusker J; Lokhorst M; Harris C; Langmuir T; Belzile E; Laizner AM; Brahim LO; Wasserman S; Chehayeb S; Vickers M; Duncan L; Esplen MJ; Maheu C; Howell D; de Raad M;

Background: Self-directed interventions are cost-effective for patients with cancer and their family caregivers, but barriers to use can compromise adherence and efficacy. Aim: Pilot a Sequential Multiple Assignment Randomized Trial (SMART) to develop a time-varying dyadic self-management interv ...

Article GUID: 39763142


Differences in Geographical Location and Health Behaviors of Participants in a Family-Based Lifestyle Intervention for Children and Adolescents Living with Obesity

Author(s): Heidl AJ; Gierc M; Saputra S; Waliwitiya T; Puterman E; Cohen TR;

It is unknown if children and youth who live in rural or "less rural" locations who enroll in the provincially funded Generation Health Clinic (British Columbia, Canada), a family-based lifestyle program for weight management, present with different health behaviors at baseline. Thus, we assessed sociodemographic and health behavior (diet, physical activi ...

Article GUID: 39761009


Young adult drinking during the COVID-19 pandemic: Examining the role of anxiety sensitivity, perceived stress, and drinking motives

Author(s): Corran C; Norman P; O' Connor RM;

Studies have shown that those high in anxiety were at increased risk for alcohol use during the COVID-19 pandemic. Tension reduction theory points to anxiety sensitivity (AS) as a potential risk factor. Drinking to cope may further increase this risk. During the pandemic, those high in AS may have experienced increased stress and drank to cope, which may ...

Article GUID: 39761074


Platform capitalisms and platform cultures

Author(s): Steinberg M; Zhang L; Mukherjee R;

This article argues for a pluralization of the "platform capitalism" framework, suggesting we should think instead in terms of "platform capitalisms." This pluralization opens the way to a better account of how platforms work in different geocultural contexts, with our focus being on China, India and Japan. The article first outlines several roles the sta ...

Article GUID: 39759402


Human Auditory-Motor Networks Show Frequency-Specific Phase-Based Coupling in Resting-State MEG

Author(s): Bedford O; Noly-Gandon A; Ara A; Wiesman AI; Albouy P; Baillet S; Penhune V; Zatorre RJ;

Perception and production of music and speech rely on auditory-motor coupling, a mechanism which has been linked to temporally precise oscillatory coupling between auditory and motor regions of the human brain, particularly in the beta frequency band. Recently, brain imaging studies using magnetoencephalography (MEG) have also shown that accurate auditory ...

Article GUID: 39757971


Evoked and entrained pupillary activity while moving to preferred tempo and beyond

Author(s): Spiech C; Hope M; Bégel V;

People synchronize their movements more easily to rhythms with tempi closer to their preferred motor rates than with faster or slower ones. More efficient coupling at one's preferred rate, compared to faster or slower rates, should be associated with lower cognitive demands and better attentional entrainment, as predicted by dynamical system theories ...

Article GUID: 39758823


Understanding the Components of Eating Behaviour-Focused Weight Management Interventions Adjunct to Metabolic Bariatric Surgery: Systematic Review of Published Literature

Author(s): Yousefi R; Ben-Porat T; O' Neill J; Boucher VG; Stojanovic J; Fortin A; Lavoie KL; Bacon SL;

Purpose of review: Eating behaviour-focused interventions are essential for improving health and weight-related outcomes in patients undergoing metabolic bariatric surgery (MBS). This work aims to examine the content of eating behaviour-focused weight management interventions adjunct to MBS in te ...

Article GUID: 39753946


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