Author(s): Sgro M; Reid ID; Arentshorst M; Ram AFJ; Tsang A;

Many microorganisms are able to use plant-derived aromatic and cyclic compounds like the common plant secondary metabolite quinic acid as carbon and energy sources. In fungi, three enzymatic steps convert quinic acid into the common intermediate protocatechuic acid, which is then further converted into TCA cycle intermediates. The genes encoding these thr ...

Article GUID: 40853219

Author(s): Khodaverdi H; Sedaghati R;

Magnetorheological (MR) foams represent a class of smart materials with unique tunable viscoelastic properties when subjected to external magnetic fields. Combining porous structures with embedded magnetic particles, these materials address challenges such as leakage and sedimentation, typically encountered in conventional MR fluids while offering advanta ...

Article GUID: 40732777

Author(s): Wu KY; Su ME; Kim Y; Nguyen L; Marchand M; Tran SD;

Wearable biosensors are revolutionizing the landscape of modern healthcare by enabling continuous, non-invasive monitoring and real-time diagnostics across a myriad of medical applications. This chapter provides a comprehensive overview of wearable biosensors, beginning with an exploration of their fundamental components, including biological elements, tr ...

Article GUID: 40683741

Author(s): Ferland MC; Wang R; Therrien-Blanchet JM; Remahi S; Côté S; Fréchette AJ; Dang-Vu TT; Liu H; Lepage JF; Théoret H;

Lorazepam is a fast-acting benzodiazepine that is widely used to manage anxiety symptoms through modulation of GABAergic activity. Despite being one of the most prescribed benzodiazepines, the effects of a single dose of lorazepam on brain functional connectivity at rest is not known. In this pla ...

Article GUID: 40646404

Author(s): Dandage R; Papkov M; Greco BM; Pereira V; Fishman D; Friesen H; Wang K; Styles EB; Kraus O; Grys B; Zapata G; Lefebvre F; Bourque G; Boone C; Andrews BJ; Parts L; Kuzmin E;

Gene duplication is common across the Tree of Life and contributes to genomic robustness. In this study, we examined changes in the subcellular localization and abundance of proteins in response to the deletion of their paralogs originating from the whole-genome duplication event, which is a larg ...

Article GUID: 40585364

Author(s): Grant N; Phillips N;

Mild cognitive impairment (MCI) and hearing loss (HL) have been separately associated with increased dementia risk. These highly co-occurring dementia risk factors are associated with aberrant functional brain connectivity. In individuals with HL aberrant functional connectivity has been associated with cognitive impairment. In individuals with MCI, aberr ...

Article GUID: 40567819

Author(s): Cai Z; Pellegrino G; Spilkin A; Delaire E; Uji M; Abdallah C; Lina JM; Fecteau S; Grova C;

Background: The relationship between task-related hemodynamic activity and brain excitability is poorly understood in humans as it is technically challenging to combine simultaneously non-invasive brain stimulation and neuroimaging modalities. Cortical excitability corresponds to the readiness to ...

Article GUID: 40567300

Author(s): Shrivastava M; Whiteway M;

In recent decades, the study of the opportunistic pathogenic fungus, Candida albicans, has been revolutionized by genomics, transforming our understanding of its molecular biology, pathogenicity, and modes of drug resistance. In this review, our effort is to trace the historical development of C. albicans research, from early clinical observations to mode ...

Article GUID: 40522159

Author(s): Sidorenkov AV; Borokhovski EF;

Article GUID: 40459704

Author(s): Delaire É; Vincent T; Cai Z; Machado A; Hugueville L; Schwartz D; Tadel F; Cassani R; Bherer L; Lina JM; Pélégrini-Issac M; Grova C;

Significance: Understanding the brain's complex functions requires multimodal approaches that combine data from various neuroimaging techniques. Functional near-infrared spectroscopy (fNIRS) offers valuable insights into hemodynamic responses, complementing other modalities such as electroenc ...

Article GUID: 40375973

Author(s): Pellerin S; Houzé B; Bedetti C; Phillips N; Brambati SM;

BackgroundMild cognitive impairment (MCI), a prodromal stage of Alzheimer's disease (AD) for many individuals, is accompanied by widespread connected speech (CS) changes (e.g., shorter CS samples, mention of fewer semantic content units, lower syntactic complexity). Nevertheless, findings on CS in MCI are heterogeneous. This heterogeneity, combined wi ...

Article GUID: 40232260