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Understanding the experience of adults with dyslexia: a quantitative and qualitative analysis

Author(s): Stark Z; Johnson AP;

Dyslexia is a neurobiological disorder characterized by persistent difficulties in reading, writing and spelling. Studying adults with dyslexia is challenging due to diverse experiences, varying ages of diagnosis and potential comorbidities. This study utilized a mixed-method approach to explore how the timing and occurrence of a dyslexia diagnosis influe ...

Article GUID: 40702374


Intolerance of uncertainty, psychological symptoms, and pain in long-term childhood cancer survivors: a report from the Childhood Cancer Survivor Study

Author(s): Alberts NM; Stratton KL; Leisenring WM; Pizzo A; Lamoureux É; Alschuler K; Flynn J; Krull KR; Jibb LA; Nathan PC; Olgin JE; Stinson JN; Armstrong GT;

Purpose: Intolerance of uncertainty is central to many psychological disorders and may contribute to pain. Despite the uncertainty inherent in childhood cancer survivorship, little is known about intolerance of uncertainty in this population. This study aimed to characterize intolerance of uncert ...

Article GUID: 40699439


24-hour activity cycle behaviors and gray matter volume in mild cognitive impairment

Author(s): Balbim GM; Boa Sorte Silva NC; Falck RS; Kramer AF; Voss MW; Liu-Ambrose T;

Introduction: The 24-hour activity cycle (24-HAC) includes physical activity (PA), sedentary behavior (SB), and sleep. The 24-HAC composition and brain health relationship in adults with mild cognitive impairment (MCI) remains underexplored. We examined associations between 24-HAC composition and gray matter (GM) volume. Methods: Cross-sectional study in ...

Article GUID: 40693459


Comparative Analysis of Preferences and Willingness to Pay for COVID-19 Vaccine Among Individuals With and Without Chronic Diseases: A Discrete Choice Experiment Approach

Author(s): Begum A; Uddin MA; Ahsan SM; Islam MA;

Background and aims: The rapid development and deployment of COVID-19 vaccines have been pivotal in the global battle against the pandemic. However, vaccine acceptance remains a critical determinant of their effectiveness. While numerous studies have explored factors influencing vaccine acceptance, there is a notable dearth of research regarding preferenc ...

Article GUID: 40687549


Impact of different acute low back pain definitions on the predictors and on the risk of transition to chronic low back pain: a prospective longitudinal cohort study

Author(s): Osagie RO; Tufa I; Angarita-Fonseca A; Pagé MG; Lacasse A; Stone LS; Rainville P; Roy M; Tétreault P; Fortin M; Léonard G; Massé-Alarie H; Roy JS; Grant AV; Meloto CB;

Inconsistencies in the identification of predictors for the transition from acute low back pain (aLBP) to chronic LBP (cLBP) may be attributed to the varying definitions of aLBP used in different studies. We investigated how adopting different aLBP definitions affects the set of predictors and th ...

Article GUID: 40663110


Microfluidic Liquid Biopsy Minimally Invasive Cancer Diagnosis by Nano-Plasmonic Label-Free Detection of Extracellular Vesicles: Review

Author(s): Neriya Hegade KP; Bhat RB; Packirisamy M;

Cancer diagnosis requires alternative techniques that allow for early, non-invasive, or minimally invasive identification. Traditional methods, like tissue biopsies, are highly invasive and can be traumatic for patients. Liquid biopsy, a less invasive option, detects cancer biomarkers in body fluids such as blood and urine. However, early-stage cancer oft ...

Article GUID: 40650129


Assessment of cognitive load in the context of neurosurgery

Author(s): Di Giovanni DA; Kersten-Oertel M; Drouin S; Collins DL;

Purpose: Image-guided neurosurgery demands precise depth perception to minimize cognitive burden during intricate navigational tasks. Existing evaluation methods rely heavily on subjective user feedback, which can be biased and inconsistent. This study uses a physiological measure via electroencephalography (EEG), to quantify cognitive load when using nov ...

Article GUID: 40650801


Deformable detection transformers for domain adaptable ultrasound localization microscopy with robustness to point spread function variations

Author(s): Gharamaleki SK; Helfield B; Rivaz H;

Super-resolution imaging has emerged as a rapidly advancing field in diagnostic ultrasound. Ultrasound Localization Microscopy (ULM) achieves sub-wavelength precision in microvasculature imaging by tracking gas microbubbles (MBs) flowing through blood vessels. However, MB localization faces challenges due to dynamic point spread functions (PSFs) caused by ...

Article GUID: 40640235


Statistical or Embodied? Comparing Colorseeing, Colorblind, Painters, and Large Language Models in Their Processing of Color Metaphors

Author(s): Nadler EO; Guilbeault D; Ringold SM; Williamson TR; Bellemare-Pepin A; Com?a IM; Jerbi K; Narayanan S; Aziz-Zadeh L;

Can metaphorical reasoning involving embodied experience-such as color perception-be learned from the statistics of language alone? Recent work finds that colorblind individuals robustly understand and reason abstractly about color, implying that color associations in everyday language might cont ...

Article GUID: 40621800


Stability of Acetals/Ketals Under Controlled Radical and Ring Opening Polymerization

Author(s): Andrade-Gagnon B; Casillas-Popova SN; Oh JK;

Well-defined acid-degradable amphiphilic block copolymers (ABPs) and their nanoassemblies labeled with acid-labile groups have been developed for smart drug delivery, exhibiting controlled/enhanced release of therapeutics in tumoral tissues and endo/lysosomes. In general, controlled polymerization techniques, particularly atom transfer radical polymerizat ...

Article GUID: 40614241


Enhanced biodegradation of crude oil by phosphate-solubilizing bacteria Bacillus subtilis PSB-1: Overcoming soluble phosphorus deficiency

Author(s): Wang X; Du Z; Li Z; Liu M; Mu J; Feng L; Chen Z; Chen Q;

Due to the oligotrophic marine environment, the lack of phosphorus is one of the key factors limiting the oil biodegradation ability of microorganisms after the oil spill occurs. Overcoming phosphorus deficiency has become an urgent problem. In this study, a phosphate-solubilizing bacteria, named Bacillus subtilis PSB-1, with the crude oil degradation eff ...

Article GUID: 40609441


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