Author(s): Meyer C; Schoettner K; Amir S;

Circadian dysfunction caused by exposure to aberrant light-dark conditions is associated with abnormal alcohol consumption in humans and animal models. Changes in drinking behavior have been linked to alterations in clock gene expression in reward-related brain areas, which could be attributed to either the effect of chronodisruption or alcohol. To date, ...

Article GUID: 39624490

Author(s): Morin CM; Vézina-Im LA; Chen SJ; Ivers H; Carney CE; Chaput JP; Dang-Vu TT; Davidson JR; Belleville G; Lorrain D; Horn O; Robillard R;

Objectives: To estimate the prevalence of insomnia and the use of sleep aids among Canadian adults. Methods: Data were derived from a phone interview conducted (April to October 2023) with a stratified, population-based sample of 4037 adults (57.6 % females; mean age 50.6 ± 18.4; range 18-102 ye ...

Article GUID: 39369578

Author(s): Casillas-Popova SN; Lokuge ND; Andrade-Gagnon B; Chowdhury FR; Skinner CD; Findlay BL; Oh JK;

Recent advances in the treatment of chronic wounds have focused on the development of effective strategies for cutting-edge wound dressings based on nanostructured materials, particularly biocompatible poly(vinyl alcohol) (PVA)-based electro-spun (e-spun) nanofibers. However, PVA nanofibers need ...

Article GUID: 38989606

Author(s): Fong JK; Mathieu Y; Vo MT; Bellemare A; Tsang A; Brumer H;

Bacterial and fungal copper radical oxidases (CROs) from Auxiliary Activity Family 5 (AA5) are implicated in morphogenesis and pathogenesis. The unique catalytic properties of CROs also make these enzymes attractive biocatalysts for the transformation of small molecules and biopolymers. Despite a recent increase in the number of characterized AA5 members, ...

Article GUID: 38953370

Author(s): Germé K; Pfaus JG;

Rationale: Alcohol can disrupt conditioned sexual inhibition (CSI) established by first-order conditioning in male rats. CSI can also be induced using second-order conditioning, during which male rats are trained to associate a neutral odor with a nonreceptive female. As a result, when given access to two receptive females (one scented and one unscented) ...

Article GUID: 38822097

Author(s): Wardell JD; Coelho SG; Farrelly KN; Fox N; Cunningham JA; O' Connor RM; Hendershot CS;

Background: Simultaneous alcohol and cannabis use is common, but observational studies examining negative consequences of simultaneous use have rarely considered dose-related interactions between alcohol and cannabis. This study examined interactions between quantities of cannabis and alcohol con ...

Article GUID: 38575530

Author(s): Mehrjou A; Hadaeghnia M; Ehsani Namin P; Ghasemi I;

Semi-interpenetrating polymer network (SIPN) hydrogels composed of sodium alginate/poly (vinyl alcohol), reinforced by PEG-grafted-graphene oxide (GO-g-PEG) were prepared by ionic crosslinking of sodium alginate. The impact of grafted PEG molecular weight with two molecular weights, i.e. 400 and 2000 g/mol, and component composition were studied on the mo ...

Article GUID: 38423903

Author(s): Ashley Reynolds

Negative affect (depression/anxiety) and alcohol use among Indigenous youth in Canada remain a concern for many communities. Disparate rates of these struggles are understood to be a potential outcome of colonization and subsequent intergenerational trauma experienced by individuals, families, and communities. Using a longitudinal design, we examined chan ...

Article GUID: 38407776

Author(s): Shrivastava M; Kouyoumdjian GS; Kirbizakis E; Ruiz D; Henry M; Vincent AT; Sellam A; Whiteway M;

Transcription factors (TFs) play key roles in cellular regulation and are critical in the control of drug resistance in the fungal pathogen Candida albicans. We found that activation of the transcription factor C4_02500C_A (Adr1) conferred significant resistance against fluconazole. In Saccharomy ...

Article GUID: 37791798

Author(s): Rigó A; Tóth-Király I; Magi A; Eisinger A; Demetrovics Z; Urbán R;

The present study was aimed at obtaining a more comprehensive understanding of the possible mediating factors in the morningness-eveningness ? alcohol consumption relation. We explored the role of mediators such as sensation seeking, the frequency of going out in the evenings, and drinking motives. We tested the proposed mediation model via structural equ ...

Article GUID: 37722395

Author(s): Dora J; Piccirillo M; Foster KT; Arbeau K; Armeli S; Auriacombe M; Bartholow B; Beltz AM; Blumenstock SM; Bold K; Bonar EE; Braitman A; Carpenter RW; Creswell KG; De Hart T; Dvorak RD; Emery N; Enkema M; Fairbairn C; Fairlie AM; Ferguson ...

Influential psychological theories hypothesize that people consume alcohol in response to the experience of both negative and positive emotions. Despite two decades of daily diary and ecological momentary assessment research, it remains unclear whether people consume more alcohol on days they exp ...

Article GUID: 37560174