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Mirtazapine for chronic insomnia in older adults: a randomised double-blind placebo-controlled trial-the MIRAGE study

Author(s): Nguyen PV; Dang-Vu TT; Forest G; Desjardins S; Forget MF; Vu TT; Nguyen QD; Kouassi E; Desmarais P;

Background: Mirtazapine promotes sleep by blocking serotonin and histaminergic receptors and is often used off-label to treat chronic insomnia. However, its efficacy remains to be demonstrated in a clinical trial. The MIRAGE study aims to determine the efficacy and safety of mirtazapine in older ...

Article GUID: 40135470


Effect of age on hypnotics' efficacy and safety in insomnia: A systematic review and meta-analysis

Author(s): Patrick Viet-Quoc N; Thien Thanh DV; Philippe L; Sebastien C; Lidia S; Philippe D;

Objective: This systematic review and meta-analysis evaluates the efficacy in improving sleep quality and safety of hypnotics in individuals aged 65 years or older compared to those under 65 years. Methods: MEDLINE, EMBASE, Web of Science, and EBM Reviews were searched for randomized clinical trials comparing hypnotics to the placebo in adults with chron ...

Article GUID: 39603114


Parental autonomy support in relation to preschool aged children's behavior: Examining positive guidance, negative control, and responsiveness

Author(s): Linkiewich D; Martinovich VV; Rinaldi CM; Howe N; Gokiert R;

This study evaluated the relationship between parental autonomy support and preschool-aged children's display of autonomy. Specifically, we examined if mothers' and fathers' use of positive guidance, negative control, and responsiveness during parent-child interactions predicted children's autonomous behavior. One hundred families comprise ...

Article GUID: 33691509


Factors influencing older adults' participation in telehealth interventions for primary prevention and health promotion: A rapid review

Author(s): Turcotte S; Bouchard C; Rousseau J; DeBroux Leduc R; Bier N; Kairy D; Dang-Vu TT; Sarimanukoglu K; Dubé F; Bourgeois Racine C; Rioux C; Shea C; Filiatrault J;

Objective: To identify facilitators and barriers to older adults' participation in telehealth interventions for primary prevention and health promotion. Methods: Relevant articles were searched using keywords in Embase and MEDLINE. Study characteristics, type of telehealth interventions and ...

Article GUID: 38014903


Rhythm and Melody Tasks for School-Aged Children With and Without Musical Training: Age-Equivalent Scores and Reliability

Author(s): Ireland K; Parker A; Foster N; Penhune V;

Measuring musical abilities in childhood can be challenging. When music training and maturation occur simultaneously, it is difficult to separate the effects of specific experience from age-based changes in cognitive and motor abilities. The goal of this study was to develop age-equivalent scores for two measures of musical ability that could be reliably ...

Article GUID: 29674984


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