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Comprehensive Analysis of Age- and Sex-Related Expression of the Chaperone Protein Sigma-1R in the Mouse Brain

Author(s): Tarmoun K; Lachance V; Le Corvec V; Bélanger SM; Beaucaire G; Kourrich S;

Sigma-1R (S1R) is a ubiquitously distributed protein highly expressed in the brain and liver. It acts as a ligand-inducible chaperone protein localized at the endoplasmic reticulum. S1R participates in several signaling pathways that oversee diverse cellula ...

Article GUID: 39335377


Overview of Sigma-1R Subcellular Specific Biological Functions and Role in Neuroprotection

Author(s): Véronik Lachance

For the past several years, fundamental research on Sigma-1R (S1R) protein has unveiled its necessity for maintaining proper cellular homeostasis through modulation of calcium and lipid exchange between the endoplasmic reticulum (ER) and mitochondria, ER-st ...

Article GUID: 36768299


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