Author(s): Sgro M; Reid ID; Arentshorst M; Ram AFJ; Tsang A;

Many microorganisms are able to use plant-derived aromatic and cyclic compounds like the common plant secondary metabolite quinic acid as carbon and energy sources. In fungi, three enzymatic steps convert quinic acid into the common intermediate protocatechuic acid, which is then further converted into TCA cycle intermediates. The genes encoding these thr ...

Article GUID: 40853219

Author(s): Moore C; Donhauser PW; Klein D; Byers-Heinlein K;

The remarkable human capacity for bilingual and multilingual acquisition raises fundamental questions about how the brain develops efficient systems for processing multiple languages. In this study, we used neural network models trained on natural speech input to examine how these efficient representations emerge. Our models show that multiple phonologica ...

Article GUID: 40828024

Author(s): Pollock D; Hasanoff S; McBride G; Kanukula R; Tricco AC; Khalil H; Campbell F; Jia RM; Alexander L; Peters M; Vieira AM; Aromataris E; Nunn J; Saran A; Evans C; Godfrey C; Pieper D; de Moraes ÉB; Biesty L; Colquhoun H; Devane D; Toomey E ...

Introduction: Scoping reviews, mapping reviews and evidence and gap maps (collectively known as 'big picture reviews') in health continue to gain popularity within the evidence ecosystem. These big-picture reviews are beneficial for policy-makers, guideline developers and researchers with ...

Article GUID: 40759523

Author(s): Keller A; Mann-Feder V; Collin-Vézina D; MacKenzie MJ;

Background: Foster care alumni face increased health challenges across the domains of mental and physical health, yet there is a paucity of research examining the associations between care experiences, health, and sleep quality in alumni aged 30 and above. Objectives: Our exploratory mixed-method study examined the sleep quality of North American group ca ...

Article GUID: 40724719

Author(s): Gilbert ML; Lewis RM; Deroche MLD; Jiam NT; Jiradejvong P; Mo J; Cooke DL; Limb CJ;

Hypothesis: To determine whether chronic use of experimental computed tomography (CT)-based frequency allocations would improve cochlear implant (CI) user performance in the areas of speech and music perception, as compared to the clinical default frequency mapping provided by the CI manufacturer. Background: CIs utilize default frequency maps to distrib ...

Article GUID: 40689899

Author(s): Neriya Hegade KP; Bhat RB; Packirisamy M;

Cancer diagnosis requires alternative techniques that allow for early, non-invasive, or minimally invasive identification. Traditional methods, like tissue biopsies, are highly invasive and can be traumatic for patients. Liquid biopsy, a less invasive option, detects cancer biomarkers in body fluids such as blood and urine. However, early-stage cancer oft ...

Article GUID: 40650129

Author(s): London-Nadeau K; Barborini C; Haines-Saah R; Bazarov M; Bristowe S; Khorkhordina M; Lemay-Gaulin M; Gorka C; Juster RP; D' Alessio H; Chadi N;

Efforts to control, repress, and punish drug use and queer and trans existence are rising as right-wing extremism becomes increasingly mainstream. These connected efforts are seen through the stifling of bodily autonomy and agency using criminal-legal, biomedical and political apparatuses, and ha ...

Article GUID: 40633507

Author(s): Thornbury M; Knoops A; Summerby-Murray I; Dhaliwal J; Johnson S; Utomo JC; Joshi J; Narcross L; Remondetto G; Pouliot M; Whiteway M; Martin VJJ;

The use of genetically modified nonconventional yeast provides significant potential for the bioeconomy by diversifying the tools available for the development of sustainable and novel products. In this study, we sequenced and annotated the genome of Kluyveromyces marxianus Y-1190 to establish it ...

Article GUID: 40629255

Author(s): Raheja Y; Singh V; Gaur VK; Tsang A; Chadha BS;

In this study, two thermostable endoglucanases (Rem_GH5EG and Rem_GH7EG) from Rasamsonia emersonii were heterologously expressed in Pichia pastoris and characterized to evaluate their potential for industrial biomass saccharification. Rem_GH5EG demonstrated markedly superior catalytic efficiency toward barley ß-glucan (kcat/Km = 6.3 × 10-3/mg mL/min), whi ...

Article GUID: 40418313

Author(s): Rosenstein B; Montpetit C; Vaillancourt N; Dover G; Weiss C; Papula LA; Melek A; Fortin M;

Low back pain (LBP) is a disabling disease and a public health concern. Aquatic exercise is an alternative form of exercise with less spinal loading and difficulty performing movements, benefiting those with pain-related fear. This study aimed to investigate the effect of an aquatic exercise prog ...

Article GUID: 40328824

Author(s): Gudymenko A; Iuliano SG; Gagnon IJ; Iverson GL; Cook NE; Zemek R; Teel EF;

Children with concussion are injured through a variety of mechanisms, but the relationship between mechanism of injury (MOI) and recovery outcomes is unclear due to small sample sizes and varied methodological designs. Our objective was to examine the association of MOI and clinical recovery in youth with concussion using a large dataset collated from a s ...

Article GUID: 40244878