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Cannabidiol and multi-modal exercise for chemotherapy-induced peripheral neuropathy in cancer survivors

Author(s): Vigano M; Kubal S; Habib S; Samarani S; Kasvis P; Koudieh N; Kilgour R; Farzin H; Ahmad A; Vigano A; Costiniuk CT;

Purpose: This study explored the effectiveness of cannabidiol (CBD) alone and in combination with multi-modal exercise (MME) to improve signs and symptoms of chemotherapy-induced peripheral neuropathy (CIPN), quality of life (QoL), and functional capacity in cancer survivors. Methods: Cancer sur ...

Article GUID: 40464985


Trilingual families language strategies: potential predictors and effect on trilingual exposure

Author(s): Quirk E; Hadeed N; Byers-Heinlein K;

Family language strategies are approaches that parents adopt for language use with their multilingual children. In bilingual contexts, these strategies influence children's language exposure and development (Macleod et al., 2022). In the more complex context of trilingualism, how families settle on strategies and their relationship with exposure may d ...

Article GUID: 40443954


Relationship Between Lumbar Multifidus Morphometry and Pain/Disability in Individuals With Chronic Nonspecific Low Back Pain After Considering Demographics, Fear-Avoidance Beliefs, Insomnia, and Spinal Degenerative Changes

Author(s): Pinto SM; Cheung JPY; Samartzis D; Karppinen J; Zheng YP; Pang MYC; Fortin M; Wong AYL;

Background: Although individuals with chronic low back pain (CLBP) show increased fatty infiltration in the lumbar multifidus muscle (LMM), it remains unclear whether LMM changes are related to clinical outcomes (such as pain and disability) after considering confounders (spinal phenotypes, fear-avoidance beliefs [FABs] and insomnia). This study examined: ...

Article GUID: 40376565


Biopsychosocial risk factors for pain in early phases of pediatric cancer treatment

Author(s): Klages KL; James RN; Kain ZN; Phipps S; Alberts NM; Fortier MA;

Introduction: Cancer pain remains a significant burden among children with cancer, and many patients experience pain starting around the time of diagnosis and throughout the course of treatment. A biopsychosocial treatment approach has been recommended to improve pain management in this population; however, specific psychosocial factors that contribute to ...

Article GUID: 40365620


Activating Group II Metabotropic Glutamate Receptors in the Basolateral Amygdala Inhibits Increases in Reward Seeking Triggered by Discriminative Stimuli in Rats

Author(s): LeCocq MR; Mainville-Berthiaume A; Laplante I; Samaha AN;

Background: Reward-associated cues guide reward-seeking behaviours. These cues include conditioned stimuli (CSs), which occur following seeking actions and predict reward delivery, and discriminative stimuli (DSs), which occur response-independently and signal that a seeking action will produce reward. Metabotropic group II glutamate (mGlu2/3) receptors i ...

Article GUID: 40341317


Distinguishing Persistent Versus Episodic Clusters of At-Risk Respondents on the Problem Gambling Severity Index

Author(s): Murch WS; Scheurich R; Monson E; French M; Kairouz S;

The Problem Gambling Severity Index (PGSI) is a popular tool for assessing past-year problems related to gambling. Multiple categorization schemes have been proposed, with scores 3-7 variously interpreted as reflecting a 'moderate' degree of problems. Crucially, it is possible to land in this Moderate-risk category by reporting one or two persiste ...

Article GUID: 40338426


Aquatic exercise versus standard care on paraspinal muscle morphology and function in chronic low back pain patients: a randomized controlled trial

Author(s): Rosenstein B; Montpetit C; Vaillancourt N; Dover G; Weiss C; Papula LA; Melek A; Fortin M;

Low back pain (LBP) is a disabling disease and a public health concern. Aquatic exercise is an alternative form of exercise with less spinal loading and difficulty performing movements, benefiting those with pain-related fear. This study aimed to investigate the effect of an aquatic exercise prog ...

Article GUID: 40328824


Experimental Investigation of the Effect of a MitraClip on Left Ventricular Flow Dynamics

Author(s): Teimouri K; Darwish A; Saleh W; Ng HD; Kadem L;

Purpose: The MitraClip device has emerged as an effective treatment option for patients with mitral regurgitation. However, implementing a MitraClip alters the mitral valve structure and left ventricular flow dynamics. In this study, we experimentally investigate the effects of the MitraClip and the resulting twin pulsed jets on flow dynamics within the l ...

Article GUID: 40325266


The false promise of return to work for migrant workers injured on the job in Canada: When public policies intersect to create exclusion

Author(s): Hanley J; Ventura Sanchez G; Goswami P; Mayell S; McLaughlin J; Hennebry J;

BackgroundMigrant workers in Canada work in the most dangerous industries, with documented difficulties with occupational health and safety (OHS) and workers' compensation (WC). Little is known, however, about migrant workers' experiences with "return-to-work", the ultimate objective of WC for those who recover from their illness or inju ...

Article GUID: 40223307


Parallel boosting neural network with mutual information for day-ahead solar irradiance forecasting

Author(s): Ahmed U; Mahmood A; Khan AR; Kuhlmann L; Alimgeer KS; Razzaq S; Aziz I; Hammad A;

The transition to sustainable energy has become imperative due to the depletion of fossil fuels. Solar energy presents a viable alternative owing to its abundance and environmental benefits. However, the intermittent nature of solar energy requires accurate forecasting of solar irradiance (SI) for reliable operation of photovoltaics (PVs) integrated syste ...

Article GUID: 40185800


Domains of wheelchair users socio-emotional experiences: Design insights from a scoping review

Author(s): Rasoulivalajoozi M; Cucuzzella C; Farhoudi M;

Background: Physical accessibility is not the only concern for wheelchair users (WUs); they also face barriers to social presence, such as challenges in social engagement and negative stereotypes. Identifying key domains in the literature that impact their social and emotional experiences is essential to addressing these issues. Objective: This scoping r ...

Article GUID: 40164524


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