Author(s): Pinto SM; Cheung JPY; Samartzis D; Karppinen J; Zheng YP; Pang MYC; Fortin M; Wong AYL;

Background: Although individuals with chronic low back pain (CLBP) show increased fatty infiltration in the lumbar multifidus muscle (LMM), it remains unclear whether LMM changes are related to clinical outcomes (such as pain and disability) after considering confounders (spinal phenotypes, fear-avoidance beliefs [FABs] and insomnia). This study examined: ...

Article GUID: 40376565

Author(s): Chen SJ; Ivers H; Dang-Vu TT; Shapiro CM; Carney CE; Robillard R; Morin CM;

Introduction: Insomnia is a prevalent yet under-characterized disorder, particularly regarding the heterogeneity of patients and their associated responses to different treatment modalities. This often leads to suboptimal management. There is a need to consider personalized approaches tailored to the characteristics of insomnia phenotypes with regard to o ...

Article GUID: 40346496

Author(s): Sforza M; Morin CM; Dang-Vu TT; Pomares FB; Perrault AA; Gouin JP; Bušková J; Janku K; Vgontzas A; Fernandez-Mendoza J; Bastien CH; Riemann D; Baglioni C; Carollo G; Casoni F; Zucconi M; Castronovo V; Galbiati A; Ferini-Strambi L;

Investigating the mechanisms of action of cognitive-behavioural therapy for insomnia (CBT-I), the first-line treatment for chronic insomnia disorder (ID), can contribute to the overall understanding of insomnia and its treatment. To date, no study has examined the relationship between K-complexes ...

Article GUID: 39739397

Author(s): Patrick Viet-Quoc N; Thien Thanh DV; Philippe L; Sebastien C; Lidia S; Philippe D;

Objective: This systematic review and meta-analysis evaluates the efficacy in improving sleep quality and safety of hypnotics in individuals aged 65 years or older compared to those under 65 years. Methods: MEDLINE, EMBASE, Web of Science, and EBM Reviews were searched for randomized clinical trials comparing hypnotics to the placebo in adults with chron ...

Article GUID: 39603114

Author(s): Chaput JP; Morin CM; Robillard R; Carney CE; Dang-Vu TT; Davidson JR; Tomkinson GR; Lang JJ;

Objective: National estimates and trends in insomnia symptoms in Canada are outdated. Updates are needed to inform the development of targeted prevention and intervention strategies. This study aimed to examine the prevalence and trends in nighttime insomnia symptoms among Canadians aged 12 years ...

Article GUID: 39556998

Author(s): Morin CM; Khullar A; Robillard R; Desautels A; Mak MSB; Dang-Vu TT; Chow W; Habert J; Lessard S; Alima L; Ayas NT; MacFarlane J; Kendzerska T; Lee EK; Carney CE;

Objective: The lack of current Canadian practice guidelines for the management of insomnia poses a challenge for healthcare providers (HCP) in selecting the appropriate treatment options. This study aimed to establish expert consensus recommendations for the management of chronic insomnia in Cana ...

Article GUID: 39481275

Author(s): Morin CM; Vézina-Im LA; Chen SJ; Ivers H; Carney CE; Chaput JP; Dang-Vu TT; Davidson JR; Belleville G; Lorrain D; Horn O; Robillard R;

Objectives: To estimate the prevalence of insomnia and the use of sleep aids among Canadian adults. Methods: Data were derived from a phone interview conducted (April to October 2023) with a stratified, population-based sample of 4037 adults (57.6 % females; mean age 50.6 ± 18.4; range 18-102 ye ...

Article GUID: 39369578

Author(s): Garneau J; Savard J; Dang-Vu TT; Gouin JP;

Objective: This study examined whether high frequency heart-rate variability (HF-HRV) and HF-HRV reactivity to worry moderate response to cognitive behavioural therapy for insomnia (CBT-I) within both a standard and stepped-care framework among cancer patients with comorbid insomnia. Biomarkers such as HF-HRV may predict response to CBT-I, a finding which ...

Article GUID: 38991424

Author(s): Dang-Vu TT; Salimi A; Boucetta S; Wenzel K; O' Byrne J; Brandewinder M; Berthomier C; Gouin JP;

Background and aim: Predisposing factors place certain individuals at higher risk for insomnia, especially in the presence of precipitating conditions such as stressful life events. Sleep spindles have been shown to play an important role in the preservation of sleep continuity. Lower spindle den ...

Article GUID: 25713529

Author(s): Gouin JP; Wenzel K; Boucetta S; O' Byrne J; Salimi A; Dang-Vu TT;

Objective: The aim of this study was to evaluate whether high-frequency heart rate variability (HF-HRV) during waking restfulness and during worry predicts increases in sleep disturbances in response to a stressful life event. Methods: A longitudinal study following up 22 individuals from well-defined periods of lower and higher stress was conducted. HF- ...

Article GUID: 25819418

Author(s): Arnold V; Ancoli-Israel S; Dang-Vu TT; Mishima K; Pinner K; Malhotra M; Moline M;

Background: Pharmacologic treatments are available to treat insomnia, a common and burdensome sleep disorder, but may be contraindicated in older adults who are prone to side effects from sleep-promoting drugs. These analyses of sleep diary data from Study E2006-G000-303 (Study 303) investigated the benefits of lemborexant 5 mg (LEM5) and 10 mg (LEM10) in ...

Article GUID: 38748321