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The role of progesterone in memory bias during spatial navigation in females

Authors: Eamonn L Gomez-Perales


Affiliations

1 Center for Studies in Behavioral Neurobiology, Department of Psychology, Concordia University, Montréal, QC, Canada.

Description

Rats can use several memory systems to navigate a maze toward a reward. Two of these are place memory and response memory and female rats can be biased to predominantly use one over another. Both progesterone and estrogens have been shown to alter memory bias. Although the effects of estrogens have been well documented, the effects of progesterone remain somewhat unexplored. Mechanisms through which progesterone may be acting to exert its effects are reviewed here. Converging evidence suggests...

Keywords: allopregnanolonedorsal striatumestrogenshippocampusprogesterone


Links

PubMed: https://pubmed.ncbi.nlm.nih.gov/36165431/

DOI: 10.1111/jne.13197