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Deep learning-based feature discovery for decoding phenotypic plasticity in pediatric high-grade gliomas single-cell transcriptomics

Author(s): Abicumaran Uthamacumaran

Advancements in AI-powered systems medicine have revolutionized biomarker discovery through emergent and explainable features. By use of complex network dynamics and graph-based machine learning, we identified critical determinants of lineage-specific plasticity across the single-cell transcriptomics of pediatric high-grade glioma (pHGGs) subtypes: IDHWT ...

Article GUID: 40848317


Artificial intelligence-assisted identification of condensing osteitis and idiopathic osteosclerosis on panoramic radiographs

Author(s): Yuksel IB; Boudesh A; Ghanbarzadehchaleshtori M; Ozsoy SC; Bahrilli S; Mohammadi R; Altindag A;

Idiopathic osteosclerosis (IOS) and condensing osteitis (CO) represent radiopaque lesions often detected incidentally within the jaws, posing substantial diagnostic challenges due to their overlapping radiographic characteristics. The objective of this study was to assess the diagnostic efficacy ...

Article GUID: 40790082


Deformable detection transformers for domain adaptable ultrasound localization microscopy with robustness to point spread function variations

Author(s): Gharamaleki SK; Helfield B; Rivaz H;

Super-resolution imaging has emerged as a rapidly advancing field in diagnostic ultrasound. Ultrasound Localization Microscopy (ULM) achieves sub-wavelength precision in microvasculature imaging by tracking gas microbubbles (MBs) flowing through blood vessels. However, MB localization faces challenges due to dynamic point spread functions (PSFs) caused by ...

Article GUID: 40640235


Comprehensive review of reinforcement learning for medical ultrasound imaging

Author(s): Elmekki H; Islam S; Alagha A; Sami H; Spilkin A; Zakeri E; Zanuttini AM; Bentahar J; Kadem L; Xie WF; Pibarot P; Mizouni R; Otrok H; Singh S; Mourad A;

Medical Ultrasound (US) imaging has seen increasing demands over the past years, becoming one of the most preferred imaging modalities in clinical practice due to its affordability, portability, and real-time capabilities. However, it faces several challenges that limit its applicability, such as ...

Article GUID: 40567264


CASCADE-FSL: Few-shot learning for collateral evaluation in ischemic stroke

Author(s): Aktar M; Tampieri D; Xiao Y; Rivaz H; Kersten-Oertel M;

Assessing collateral circulation is essential in determining the best treatment for ischemic stroke patients as good collaterals lead to different treatment options, i.e., thrombectomy, whereas poor collaterals can adversely affect the treatment by leading to excess bleeding and eventually death. To reduce inter- and intra-rater variability and save time ...

Article GUID: 40250214


Large language models deconstruct the clinical intuition behind diagnosing autism

Author(s): Stanley J; Rabot E; Reddy S; Belilovsky E; Mottron L; Bzdok D;

Efforts to use genome-wide assays or brain scans to diagnose autism have seen diminishing returns. Yet the clinical intuition of healthcare professionals, based on longstanding first-hand experience, remains the gold standard for diagnosis of autism. We leveraged deep learning to deconstruct and interrogate the logic of expert clinician intuition from cli ...

Article GUID: 40147442


Leveraging deep learning for nonlinear shape representation in anatomically parameterized statistical shape models

Author(s): Gheflati B; Mirzaei M; Rottoo S; Rivaz H;

Purpose: Statistical shape models (SSMs) are widely used for morphological assessment of anatomical structures. However, a key limitation is the need for a clear relationship between the model's shape coefficients and clinically relevant anatomical parameters. To address this limitation, this paper proposes a novel deep learning-based anatomically par ...

Article GUID: 39953355


In Shift and In Variance: Assessing the Robustness of HAR Deep Learning Models Against Variability

Author(s): Khaked AA; Oishi N; Roggen D; Lago P;

Deep learning (DL)-based Human Activity Recognition (HAR) using wearable inertial measurement unit (IMU) sensors can revolutionize continuous health monitoring and early disease prediction. However, most DL HAR models are untested in their robustness to real-world variability, as they are trained on limited lab-controlled data. In this study, we isolated ...

Article GUID: 39860799


A protocol for trustworthy EEG decoding with neural networks

Author(s): Borra D; Magosso E; Ravanelli M;

Deep learning solutions have rapidly emerged for EEG decoding, achieving state-of-the-art performance on a variety of decoding tasks. Despite their high performance, existing solutions do not fully address the challenge posed by the introduction of many hyperparameters, defining data pre-processing, network architecture, network training, and data augment ...

Article GUID: 39549492


Near-optimal learning of Banach-valued, high-dimensional functions via deep neural networks

Author(s): Adcock B; Brugiapaglia S; Dexter N; Moraga S;

The past decade has seen increasing interest in applying Deep Learning (DL) to Computational Science and Engineering (CSE). Driven by impressive results in applications such as computer vision, Uncertainty Quantification (UQ), genetics, simulations and image processing, DL is increasingly supplanting classical algorithms, and seems poised to revolutionize ...

Article GUID: 39454372


Deep neural network-based robotic visual servoing for satellite target tracking

Author(s): Ghiasvand S; Xie WF; Mohebbi A;

In response to the costly and error-prone manual satellite tracking on the International Space Station (ISS), this paper presents a deep neural network (DNN)-based robotic visual servoing solution to the automated tracking operation. This innovative approach directly addresses the critical issue of motion decoupling, which poses a significant challenge in ...

Article GUID: 39440297


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