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Comprehensive Analysis of Age- and Sex-Related Expression of the Chaperone Protein Sigma-1R in the Mouse Brain

Author(s): Tarmoun K; Lachance V; Le Corvec V; Bélanger SM; Beaucaire G; Kourrich S;

Sigma-1R (S1R) is a ubiquitously distributed protein highly expressed in the brain and liver. It acts as a ligand-inducible chaperone protein localized at the endoplasmic reticulum. S1R participates in several signaling pathways that oversee diverse cellula ...

Article GUID: 39335377


Impact of Stimulation Frequency on Verbal Fluency Following Bilateral Subthalamic Nucleus Deep Brain Stimulation in Parkinson's Disease

Author(s): Busteed L; García-Sánchez C; Pascual-Sedano B; Grunden N; Gironell A; Kulisevsky J; Pagonabarraga J; ...

Objective: The effects of stimulation frequency on verbal fluency (VF) following subthalamic nucleus deep brain stimulation (STN-DBS) in Parkinson's disease (PD) are not well understood. The pr ...

Article GUID: 39127889


Feasibility and acceptability of an adapted peer-based walking intervention for adults with moderate-to-severe traumatic brain injury

Author(s): Quilico EL; Wilkinson S; Duncan LR; Sweet SN; Alarie C; Bédard E; Gheta I; Brodeur CL; Colantonio A; Swaine BR; ...

Purpose: To examine the feasibility and acceptability of a 6-week peer-based walking intervention for adults with moderate-to-severe TBI with telehealth supports. Materials and methods: Pre-post f ...

Article GUID: 39051571


Open access segmentations of intraoperative brain tumor ultrasound images

Author(s): Behboodi B; Carton FX; Chabanas M; de Ribaupierre S; Solheim O; Munkvold BKR; Rivaz H; Xiao Y; Reinertsen I; ...

Purpose: Registration and segmentation of magnetic resonance (MR) and ultrasound (US) images could play an essential role in surgical planning and resectioning brain tumors. However, validating the ...

Article GUID: 39047165


The BDNF Val66Met polymorphism and health-related quality of life in youth with obesity

Author(s): Goldfield GS; Cameron JD; Sigal RJ; Kenny GP; Prud' homme D; Ngu M; Alberga AS; Doucette S; Goldfield DB; Tulloch H; Thai H; Simas KR; ...

The brain derived-neurotrophic factor (BDNF) Val66Met polymorphism causes functional changes in BDNF, and is associated with obesity and some psychiatric disorders, but its relationship to health-r ...

Article GUID: 38997217


EEG/MEG source imaging of deep brain activity within the maximum entropy on the mean framework: Simulations and validation in epilepsy

Author(s): Afnan J; Cai Z; Lina JM; Abdallah C; Delaire E; Avigdor T; Ros V; Hedrich T; von Ellenrieder N; Kobayashi E; Frauscher B; Gotman J; Grova C; ...

Electro/Magneto-EncephaloGraphy (EEG/MEG) source imaging (EMSI) of epileptic activity from deep generators is often challenging due to the higher sensitivity of EEG/MEG to superficial regions and t ...

Article GUID: 38994740


Cross-modal plasticity in children with cochlear implant: converging evidence from EEG and functional near-infrared spectroscopy

Author(s): Deroche MLD; Wolfe J; Neumann S; Manning J; Hanna L; Towler W; Wilson C; Bien AG; Miller S; Schafer E; Gemignani J; Alemi R; Muthuraman M; K ...

Over the first years of life, the brain undergoes substantial organization in response to environmental stimulation. In a silent world, it may promote vision by (i) recruiting resources from the au ...

Article GUID: 38846536


Language Exposure and Brain Myelination in Early Development

Author(s): Fibla L; Forbes SH; McCarthy J; Mee K; Magnotta V; Deoni S; Cameron D; Spencer JP;

The language environment to which children are exposed has an impact on later language abilities as well as on brain development; however, it is unclear how early such impacts emerge. This study investigates the effects of children's early language envi ...

Article GUID: 37188518


Computational neuroscience across the lifespan: Promises and pitfalls

Author(s): van den Bos W; Bruckner R; Nassar MR; Mata R; Eppinger B;

In recent years, the application of computational modeling in studies on age-related changes in decision making and learning has gained in popularity. One advantage of computational models is that they provide access to latent variables that cannot be direc ...

Article GUID: 29066078


Athlete Fear Avoidance, Depression, and Anxiety Are Associated with Acute Concussion Symptoms in Athletes

Author(s): Patlan I; Gamelin G; Khalaj K; Castonguay T; Dover G;

ackground: Assessing sport-related concussions in athletes presents challenges due to symptom variability. This study aimed to explore the relationship between acute concussion symptoms and athlete fear avoidance, pain catastrophizing, depression, and anxie ...

Article GUID: 38673675


Brain tumor detection based on a novel and high-quality prediction of the tumor pixel distributions

Author(s): Sun Y; Wang C;

The work presented in this paper is in the area of brain tumor detection. We propose a fast detection system with 3D MRI scans of Flair modality. It performs 2 functions, predicting the gray level distribution and location distribution of the pixels in the ...

Article GUID: 38493601


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