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Trilingual families language strategies: potential predictors and effect on trilingual exposure

Author(s): Quirk E; Hadeed N; Byers-Heinlein K;

Family language strategies are approaches that parents adopt for language use with their multilingual children. In bilingual contexts, these strategies influence children's language exposure and development (Macleod et al., 2022). In the more complex context of trilingualism, how families settle on strategies and their relationship with exposure may d ...

Article GUID: 40443954


Emerging Image-Guided Navigation Techniques for Cardiovascular Interventions: A Scoping Review

Author(s): Roshanfar M; Salimi M; Jang SJ; Sinusas AJ; Kim J; Mosadegh B;

Background: Image-guided navigation has revolutionized precision cardiac interventions, yet current technologies face critical limitations in real-time guidance and procedural accuracy. Method: Here, we comprehensively evaluate state-of-the-art imaging modalities, from conventional fluoroscopy to emerging hybrid systems, analyzing their applications acros ...

Article GUID: 40428106


The enterobactin biosynthetic intermediate 2,3-dihydroxybenzoic acid is a competitive inhibitor of the Escherichia coli isochorismatase EntB

Author(s): Bin X; Pawelek PD;

The Escherichia coli enterobactin biosynthetic protein EntB is a bifunctional enzyme that catalyzes hydrolysis of isochorismate via its N-terminal isochorismatase (IC) domain, and then transfers phosphopantetheinylated 2,3-DHB to EntF via the EntB C-terminal aryl carrier protein (ArCP) domain. Here we used a fluorescence anisotropy binding assay to invest ...

Article GUID: 40400396


Investigation of Phase-Change Droplets and Fast Imaging for Indicator Dilution Measurement of Flow

Author(s): Zajac Z; Helfield B; Williams R; Sheeran P; Tremblay-Darveau C; Yoo K; Burns PN;

Objectives: The development of low boiling point liquid droplets as phase-change contrast agents allows for the local creation of microbubbles at a point of interest in vivo. Although there are many possible applications, few investigations have used selectively created microbubble boluses to measure volumetric flowrate. In this study, the flow ratio betw ...

Article GUID: 40387284


NIRSTORM: a Brainstorm extension dedicated to functional near-infrared spectroscopy data analysis, advanced 3D reconstructions, and optimal probe design

Author(s): Delaire É; Vincent T; Cai Z; Machado A; Hugueville L; Schwartz D; Tadel F; Cassani R; Bherer L; Lina JM; Pélégrini-Issac M; Grova C;

Significance: Understanding the brain's complex functions requires multimodal approaches that combine data from various neuroimaging techniques. Functional near-infrared spectroscopy (fNIRS) offers valuable insights into hemodynamic responses, complementing other modalities such as electroenc ...

Article GUID: 40375973


Biopsychosocial risk factors for pain in early phases of pediatric cancer treatment

Author(s): Klages KL; James RN; Kain ZN; Phipps S; Alberts NM; Fortier MA;

Introduction: Cancer pain remains a significant burden among children with cancer, and many patients experience pain starting around the time of diagnosis and throughout the course of treatment. A biopsychosocial treatment approach has been recommended to improve pain management in this population; however, specific psychosocial factors that contribute to ...

Article GUID: 40365620


Children s attribution of mental states to humans and social robots assessed with the Theory of Mind Scale

Author(s): Goldman EJ; Baumann AE; Pare L; Beaudoin J; Poulin-Dubois D;

The present work examined children's attribution of psychological properties to inanimate agents in two experiments. In Study 1, an Interview Task and the Theory of Mind Scale (ToM Scale) were administered to 4-year-olds with either a human or a humanoid robot (NAO) protagonist. Parents also completed the Children's Social Understanding Scale (CSU ...

Article GUID: 40348850


Experimental Investigation of the Effect of a MitraClip on Left Ventricular Flow Dynamics

Author(s): Teimouri K; Darwish A; Saleh W; Ng HD; Kadem L;

Purpose: The MitraClip device has emerged as an effective treatment option for patients with mitral regurgitation. However, implementing a MitraClip alters the mitral valve structure and left ventricular flow dynamics. In this study, we experimentally investigate the effects of the MitraClip and the resulting twin pulsed jets on flow dynamics within the l ...

Article GUID: 40325266


Connected speech profiles in mild cognitive impairment reflect global cognition

Author(s): Pellerin S; Houzé B; Bedetti C; Phillips N; Brambati SM;

BackgroundMild cognitive impairment (MCI), a prodromal stage of Alzheimer's disease (AD) for many individuals, is accompanied by widespread connected speech (CS) changes (e.g., shorter CS samples, mention of fewer semantic content units, lower syntactic complexity). Nevertheless, findings on CS in MCI are heterogeneous. This heterogeneity, combined wi ...

Article GUID: 40232260


Large language models deconstruct the clinical intuition behind diagnosing autism

Author(s): Stanley J; Rabot E; Reddy S; Belilovsky E; Mottron L; Bzdok D;

Efforts to use genome-wide assays or brain scans to diagnose autism have seen diminishing returns. Yet the clinical intuition of healthcare professionals, based on longstanding first-hand experience, remains the gold standard for diagnosis of autism. We leveraged deep learning to deconstruct and interrogate the logic of expert clinician intuition from cli ...

Article GUID: 40147442


Mirtazapine for chronic insomnia in older adults: a randomised double-blind placebo-controlled trial-the MIRAGE study

Author(s): Nguyen PV; Dang-Vu TT; Forest G; Desjardins S; Forget MF; Vu TT; Nguyen QD; Kouassi E; Desmarais P;

Background: Mirtazapine promotes sleep by blocking serotonin and histaminergic receptors and is often used off-label to treat chronic insomnia. However, its efficacy remains to be demonstrated in a clinical trial. The MIRAGE study aims to determine the efficacy and safety of mirtazapine in older ...

Article GUID: 40135470


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