Author(s): Spiegler P; Abdelsalam H; Hellum O; Hadjinicolaou A; Weil AG; Xiao Y;

Epilepsy is a neurological disorder characterized by recurring seizures that can cause a wide range of symptoms. Stereo-electroencephalography (SEEG) is a diagnostic procedure where multiple electrodes are stereotactically implanted within predefined brain regions to identify the seizure onset zone, which needs to be surgically removed or disconnected to ...

Article GUID: 39735694

Author(s): Ghazikhani H; Butler G;

Ion channels are critical membrane proteins that regulate ion flux across cellular membranes, influencing numerous biological functions. The resource-intensive nature of traditional wet lab experiments for ion channel identification has led to an increasing emphasis on computational techniques. This study extends our previous work on protein language mode ...

Article GUID: 39572876

Author(s): Morin CM; Vézina-Im LA; Chen SJ; Ivers H; Carney CE; Chaput JP; Dang-Vu TT; Davidson JR; Belleville G; Lorrain D; Horn O; Robillard R;

Objectives: To estimate the prevalence of insomnia and the use of sleep aids among Canadian adults. Methods: Data were derived from a phone interview conducted (April to October 2023) with a stratified, population-based sample of 4037 adults (57.6 % females; mean age 50.6 ± 18.4; range 18-102 ye ...

Article GUID: 39369578

Author(s): Bin X; Pawelek PD;

Enterobactin is a high-affinity iron chelator produced and secreted by Escherichia coli and Salmonella typhimurium to scavenge scarce extracellular Fe3+ as a micronutrient. EntC and EntB are the first two enzymes in the enterobactin biosynthetic pathway. Isochorismate, produced by EntC, is a substrate for EntB isochorismatase. By using a competing isochor ...

Article GUID: 39031458

Author(s): London-Nadeau K; Lafortune C; Gorka C; Lemay-Gaulin M; Séguin J; Haines-Saah R; Ferlatte O; Chadi N; Juster RP; Bristowe S; D' Alessio H; Bernal L; Ellis-Durity K; Barbosa J; Da Costa De Carlos LAAC; Castellanos Ryan N;

Background: Queer and trans (QT) youth report higher rates of cannabis use than their cisgender and heterosexual peers. Explanations for this have overwhelmingly focused on the difficulties QT youth face, while little research has examined how cannabis use can relate to QT youth's strengths. ...

Article GUID: 38991874

Author(s): Mosley JD; Dunn WB; Kuligowski J; Lewis MR; Monge ME; Ulmer Holland C; Vuckovic D; Zanetti KA; Schock TB;

Introduction: During the Metabolomics 2023 conference, the Metabolomics Quality Assurance and Quality Control Consortium (mQACC) presented a QA/QC workshop for LC-MS-based untargeted metabolomics. Objectives: The Best Practices Working Group disseminated recent findings from community forums and ...

Article GUID: 38980450

Author(s): Xue X; Yuan B; Yi Y; Zhang Y; Yue X; Mu L;

This paper proposes a novel multi-unmanned aerial vehicle (UAV) connectivity preservation controller, suitable for scenarios with bounded actuation and limited communication range. According to the hierarchical control strategy, controllers are designed separately for the position and attitude subsystems. A distributed position controller is developed, in ...

Article GUID: 38964998

Author(s): Kazemipour N; Hooshiar A; Kersten-Oertel M;

Purpose: Proper visualization and interaction with complex anatomical data can improve understanding, allowing for more intuitive surgical planning. The goal of our work was to study what the most intuitive yet practical platforms for interacting with 3D medical data are in the context of surgical planning. Methods: We compared planning using a monitor a ...

Article GUID: 38942947

Author(s): Ghazikhani H; Butler G;

This study introduces TooT-PLM-ionCT, a comprehensive framework that consolidates three distinct systems, each meticulously tailored for one of the following tasks: distinguishing ion channels (ICs) from membrane proteins (MPs), segregating ion transporters (ITs) from MPs, and differentiating ICs from ITs. Drawing upon the strengths of six Protein Languag ...

Article GUID: 38656743

Author(s): Valikhanova G; Kato Y; Fitzcharles MA; Ware M; Da Costa D; Lowensteyn I; Cheung HS; Grover S;

Background: Medical cannabis (MC) is used by Canadian Veterans to manage a wide range of health issues. However, there is little information comparing the reasons for MC use and its perceived effectiveness between Veterans and non-Veterans. Objects: We compared MC use among a convenience sample ...

Article GUID: 37920683

Author(s): Arentshorst M; Falco MD; Moisan MC; Reid ID; Spaapen TOM; van Dam J; Demirci E; Powlowski J; Punt PJ; Tsang A; Ram AFJ;

Tannic acid, a hydrolysable gallotannin present in plant tissues, consists of a central glucose molecule esterified with gallic acid molecules. Some microorganisms, including several Aspergillus species, can metabolize tannic acid by releasing gallic acid residues from tannic acid by secreting ta ...

Article GUID: 37744122