Author(s): Spence DS; Painter KJ; Nazemi A; Venkiteswaran JJ; Baulch HM;

Drinking water treatability is defined by multiple parameters that are strongly impacted by climatic and anthropogenic drivers. Working in a shallow reservoir in the Canadian Prairies, generalized additive models (GAMs) were applied to a 33-year dataset to identify drivers of interannual variability in multiple indicators of drinking water treatability. I ...

Article GUID: 41166973

Author(s): Grant KR; Kembel SW; Naik S; Dayanandan S;

Endophytes asymptomatically infect virtually all plant species, yet little is known about endophyte community assembly and diversity within the woody tissues of forest trees. We utilised phylogenetic null models of alpha (ses.MNTDab and ses.MPDab) and beta diversity (ses.ßMNTDab and ses.ßMPDab) to infer the role of deterministic and stochastic ecological ...

Article GUID: 41089252

Author(s): Francavilla R; Chattopadhyaya B; Damo Kamda JL; Jadhav V; Kourrich S; Michaud JL; Di Cristo G;

SYNGAP1 haploinsufficiency-related intellectual disability (SYNGAP1-ID) is characterized by moderate to severe ID, generalized epilepsy, autism spectrum disorder, sensory processing dysfunction, and other behavioral abnormalities. While numerous studies have highlighted a role of Syngap1 in corti ...

Article GUID: 40810392

Author(s): Kairouz S; Savard AC; Murch WS; Dixon MR; Martin NB; Brodeur M; Dauphinais S; Ferland F; Hamel D; Dufour M; French M; Monson E; Van Mourik V; Morvannou A;

Background: The COVID-19 pandemic brought about an extraordinary societal context in which the gambling offer was modified to meet public health measures intended to curb viral transmission. With many land-based gambling venues being forced to close, gambling opportunities were left almost exclus ...

Article GUID: 40770758

Author(s): Begum A; Uddin MA; Ahsan SM; Islam MA;

Background and aims: The rapid development and deployment of COVID-19 vaccines have been pivotal in the global battle against the pandemic. However, vaccine acceptance remains a critical determinant of their effectiveness. While numerous studies have explored factors influencing vaccine acceptance, there is a notable dearth of research regarding preferenc ...

Article GUID: 40687549

Author(s): Memari E; Singh D; Alkins R; Helfield B;

Cellular immunotherapy remains hindered in the context of solid tumors due to the immunosuppressive microenvironment, in which key endothelial cell adhesion molecules (CAM) are suppressed. Microbubble-mediated focused ultrasound is being explored for targeted immunotherapy and can exert local shear stress upon neighboring endothelial cells. However, fluid ...

Article GUID: 40657183

Author(s): Campbell JR; Russell WA; Wagner CE; Manuel DG; Anipindi V; Baral P; Evans TG; Hankins CA; Sander B;

The Government of Canada, through the COVID-19 Immunity Task Force (CITF), supported over 100 serosurveillance studies during the COVID-19 pandemic, building and strengthening the technical infrastructure necessary for a national serosurveillance network. The value of such a network extends beyon ...

Article GUID: 40588636

Author(s): Ren C; Cao SJ; Haghighat F;

During the ongoing COVID-19 pandemic period, the airborne transmission of viruses has raised widespread concern as daily activities are resumed in public buildings. It is essential to develop mitigation strategies of infection disease transmission (e.g., increase of ventilation rate) in different scenarios to reduce the infection risk. For classrooms in s ...

Article GUID: 40477856

Author(s): Rayegan S; Shu C; Berquist J; Jeon J; Zhou LG; Wang LL; Mbareche H; Tardif P; Ge H;

In the past few years, significant efforts have been made to investigate the transmission of COVID-19. This paper provides a review of the COVID-19 airborne transmission modeling and mitigation strategies. The simulation models here are classified into airborne transmission infectious risk models and numerical approaches for spatiotemporal airborne transm ...

Article GUID: 40478135

Author(s): Eskandari K; Bélanger SM; Lachance V; Kourrich S;

Neurodegenerative disorders, such as Alzheimer's, Parkinson's, and Huntington's disease, due to their multifaced and complicated nature, remain uncurable and impose substantial financial and human burdens on society. Therefore, developing new innovative therapeutic strategies is vital. In this context, drug repurposing has emerged as a promisi ...

Article GUID: 40430519

Author(s): Sanami S; Intzandt B; Huck J; Villeneuve S; Iturria-Medina Y; Gauthier CJ; Prevent-Ad Research Group None;

Alzheimer's disease (AD) is a complex disease that involves complex interactions between protein biomarkers such as amyloid beta (Aß) and tau, neurodegeneration, cerebrovascular health and inflammation. However, how these factors interact, especially in the early phases of disease development ...

Article GUID: 40347524