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Overweight and obesity in early childhood and obesity at 10 years of age: a comparison of World Health Organization definitions

Author(s): Van Hulst A; Zheng S; Argiropoulos N; Ybarra M; Ball GDC; Kakinami L;

The World Health Organization recommends using + 2 SD of body mass index z-score (zBMI) to define overweight/obesity (OWO) in children ages 2 to 5 years whereas + 1 SD is used as cut-point from 5 years onwards. Empirical evidence for using different cut-points across childhood is lacking. Our objective was to compare the ability of OWO in early childhood ...

Article GUID: 40140102


Sex-specific effects of intensity and dose of physical activity on BOLD-fMRI cerebrovascular reactivity and cerebral pulsatility

Author(s): Potvin-Jutras Z; Intzandt B; Mohammadi H; Liu P; Chen JJ; Gauthier CJ;

Cerebrovascular reactivity (CVR) and cerebral pulsatility (CP) are important indicators of cerebrovascular health, which are associated with physical activity (PA). While sex differences influence the impact of PA on cerebrovascular health, sex-specific effects of PA intensity and dose on CP and CVR remains unknown. This study aimed to evaluate the sex-sp ...

Article GUID: 40079560


Comparison of Combined Motor Control Training and Isolated Extensor Strengthening Versus General Exercise on Lumbar Paraspinal Muscle Health and Associations With Patient-Reported Outcome Measures in Chronic Low Back Pain Patients: A Randomized Controlled Trial

Author(s): Rosenstein B; Rye M; Roussac A; Naghdi N; Macedo LG; Elliott J; DeMont R; Weber MH; Pepin V; Dover G; Fortin M;

Study DesignProspective Randomized Controlled Trial.ObjectivesTo investigate the effect of combined motor control and isolated lumbar strengthening exercise (MC + ILEX) vs general exercise (GE) on upper lumbar paraspinal muscle volume and composition, strength and patient outcomes in individuals ...

Article GUID: 40066720


Combating childhood overweight and obesity: The role of Olympic Movement and bodily movement

Author(s): Tam BT; Wan K; Santosa S; Cai Z;

With over 420 million children (aged 0-19 years) worldwide living with overweight or obesity, the "obesity epidemic" or "globesity" is a defining public health challenge of this generation. While significant efforts have been made to address obesity in adults, less attention has been given to the critical issue of childhood overweight and ...

Article GUID: 39991475


A database of magnetic resonance imaging-transcranial ultrasound co-registration

Author(s): Alizadeh M; Collins DL; Kersten-Oertel M; Xiao Y;

Purpose: As a portable and cost-effective imaging modality with better accessibility than Magnetic Resonance Imaging (MRI), transcranial sonography (TCS) has demonstrated its flexibility and potential utility in various clinical diagnostic applications, including Parkinson's disease and cerebrovascular conditions. To better understand the information ...

Article GUID: 39920905


Sex differences in the metabolism of glucose and fatty acids by adipose tissue and skeletal muscle in humans

Author(s): Costa DN; Santosa S; Jensen MD;

Adult males and females have markedly different body composition, energy expenditure, and have different degrees of risk for metabolic diseases. A major aspect of metabolic regulation involves the appropriate storage and disposal of glucose and fatty acids. The use of sophisticated calorimetry, tracer, and imaging techniques have provided insight into the ...

Article GUID: 39869194


Dialogue mechanisms between astrocytic and neuronal networks: A whole-brain modelling approach

Author(s): Ali OBK; Vidal A; Grova C; Benali H;

Astrocytes critically shape whole-brain structure and function by forming extensive gap junctional networks that intimately and actively interact with neurons. Despite their importance, existing computational models of whole-brain activity ignore the roles of astrocytes while primarily focusing on neurons. Addressing this oversight, we introduce a biophys ...

Article GUID: 39804928


Patterns of Cerebellar-Cortical Structural Covariance Mirror Anatomical Connectivity of Sensorimotor and Cognitive Networks

Author(s): Alasmar Z; Chakravarty MM; Penhune VB; Steele CJ;

The cortex and cerebellum are densely connected through reciprocal input/output projections that form segregated circuits. These circuits are shown to differentially connect anterior lobules of the cerebellum to sensorimotor regions, and lobules Crus I and II to prefrontal regions. This differential connectivity pattern leads to the hypothesis that indivi ...

Article GUID: 39791308


Cognitive-behavioural therapy for insomnia mechanism of action: Exploring the homeostatic K-complex involvement

Author(s): Sforza M; Morin CM; Dang-Vu TT; Pomares FB; Perrault AA; Gouin JP; Bušková J; Janku K; Vgontzas A; Fernandez-Mendoza J; Bastien CH; Riemann D; Baglioni C; Carollo G; Casoni F; Zucconi M; Castronovo V; Galbiati A; Ferini-Strambi L;

Investigating the mechanisms of action of cognitive-behavioural therapy for insomnia (CBT-I), the first-line treatment for chronic insomnia disorder (ID), can contribute to the overall understanding of insomnia and its treatment. To date, no study has examined the relationship between K-complexes ...

Article GUID: 39739397


Metrics for evaluation of automatic epileptogenic zone localization in intracranial electrophysiology

Author(s): Hrtonova V; Nejedly P; Travnicek V; Cimbalnik J; Matouskova B; Pail M; Peter-Derex L; Grova C; Gotman J; Halamek J; Jurak P; Brazdil M; Klimes P; Frauscher B;

Introduction: Precise localization of the epileptogenic zone is critical for successful epilepsy surgery. However, imbalanced datasets in terms of epileptic vs. normal electrode contacts and a lack of standardized evaluation guidelines hinder the consistent evaluation of automatic machine learnin ...

Article GUID: 39608298


Feeling safe: a critical look at the effect of neighborhood safety features and perceptions on childhood symptoms of depression

Author(s): Infantino E; Barnett TA; Côté-Lussier C; Van Hulst A; Henderson M; Mathieu ME; Sabiston C; Kakinami L;

Background: Physical characteristics and perceptions of an environment can have enduring effects on one's mental health. The present study aimed to determine whether a set of measures of neighborhood safety - independent built environment features, parents' perception of neighborhood safe ...

Article GUID: 39604905


The Immediate Effect of a Single Treatment of Neuromuscular Electrical Stimulation with the StimaWELL 120MTRS System on Multifidus Stiffness in Patients with Chronic Low Back Pain

Author(s): Wolfe D; Dover G; Boily M; Fortin M;

Background/objectives: Individuals with chronic low back pain (CLBP) have altered lumbar multifidus stiffness properties compared to healthy controls. Although neuromuscular electrical stimulation (NMES) application to the multifidus might affect stiffness, this has never been investigated. The aims of this study were to examine the effect of a single NME ...

Article GUID: 39594260


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