Author(s): Goulet D; Boivin M; Gravel C; Little J; Ouellet-Morin I; Gouin JP; Dubois L;
The lack of polygenic scores (PGSs) developed for body-mass index (BMI) in children may be problematic because the genetic architecture characterizing BMI changes throughout life. This study aims to describe the genetic susceptibility to obesity in children and to compare two PGSs based on data from adults and children and their association with BMI and d ...
Article GUID: 40132211
Author(s): Bögershausen N; Cavdarli B; Nagai T; Milev MP; Wolff A; Mehranfar M; Schmidt J; Choudhary D; Gutiérrez-Gutiérrez Ó; Cyganek L; Saint-Dic D; Zibat A; Köhrer K; Wollenweber TE; Wieczorek D; Altmüller J; Borodina T; Kaçar D; Haliloglu G; Li ...
As a major component of intracellular trafficking, the coat protein complex II (COPII) is indispensable for cellular function during embryonic development and throughout life. The four SEC24 proteins (A-D) are essential COPII components involved in cargo selection and packaging. A human disorder ...
Article GUID: 40131364
Author(s): Hervé V; Bonenfant L; Amyot M; Balafrej R; Ali OBK; Benali H; Brouillette J;
In Alzheimer's disease, there is an imbalance in neurotransmitter release and altered neuronal activation. Here, we present a protocol approach to analyze neuronal activity by combining local field potential (LFP) recording with microdialysis within the same animal. We describe steps for measuring glutamate and GABA levels following hippocampal amyloi ...
Article GUID: 40131934
Author(s): Avigdor T; Ren G; Abdallah C; Dubeau F; Grova C; Frauscher B;
Morning awakening is part of everyday life. Surprisingly, information remains scarce on its underlying neurophysiological correlates. Here simultaneous polysomnography and stereo-electroencephalography recordings from 18 patients are used to assess the spectral and connectivity content of the process of awakening at a local level 15 min before and after t ...
Article GUID: 40126936
Author(s): Bokhari R; Bisson DG; Fortin M; Vigouroux M; Cata JP; Hwang KP; Chen MM; Ceniza-Bordallo G; Ouellet JA; Ingelmo PM;
Introduction: Pain in lower back is a common condition reported by astronauts, both during and after space missions. Investigating the alterations in the spine and the mechanisms driving these changes is essential for a deeper understanding of how microgravity impacts the human spine. This knowle ...
Article GUID: 40124538
Author(s): Aïmen E Gheribi
In recent years, there has been a renewed interest in accurately quantifying the ion's transference number within molten salts. Surprisingly, despite efforts to address the severe lack of experimental data, there is still no reliable theoretical framework that establishes a clear link between the transference number and simulated phase trajectories th ...
Article GUID: 40124059
Author(s): Sun Y; Bakhtiari S; Valente-Paterno M; Jiang H; Zerges W;
A small genome in chloroplasts encodes many of the polypeptide subunits of the photosynthetic electron transport complexes embedded in the membranes of thylakoid vesicles in the chloroplast stroma and synthesized by ribosomes of the bacterial-like genetic system of this semiautonomous organelle. While thylakoid membranes are sites of translation, evidence ...
Article GUID: 40116843
Author(s): Bouchard R; Babin C; Normandeau E; Xuereb A; Boulanger F; Coxon A; Diamond S; Fireman R; Lameboy J; Louttit N; Natawapineskum G; Okimaw D; Torio D; Varty S; Moore JS; Fraser D; Bernatchez L;
Dispersal is a highly variable trait influenced by life history and ecological factors, affecting gene flow when dispersers successfully reproduce. Anadromous salmonids, with their diverse migratory strategies and ecological traits, serve as an ideal model for studying dispersal evolution, showca ...
Article GUID: 40108992
Author(s): Elmekki H; Alagha A; Sami H; Spilkin A; Zanuttini AM; Zakeri E; Bentahar J; Kadem L; Xie WF; Pibarot P; Mizouni R; Otrok H; Singh S; Mourad A;
Cardiac ultrasound (US) scanning is one of the most commonly used techniques in cardiology to diagnose the health of the heart and its proper functioning. During a typical US scan, medical professionals take several images of the heart to be classified based on the cardiac views they contain, wit ...
Article GUID: 40107020
Author(s): Zhao M; Law A; Su C; Jennings S; Bourgon A; Jia W; Larose MH; Bowness D; Zeng Y;
Objective: This study aims to investigate the relationship between the subjective performance evaluations on pilot trainees' aircraft control abilities and their brainwave dynamics reflected in the results from EEG microstate analysis. Specifically, we seek to identify correlations between distinct microstate patterns and each dimension included in th ...
Article GUID: 40109507
Author(s): Xing C; Ge J; Chen R; Li S; Wang C; Zhang X; Geng Y; Jones KC; Zhu Y;
Organophosphate esters (OPEs) raise growing environmental and human health concerns globally. However, numerous novel OPEs lack data on physicochemical properties, which are essential for assessing environmental fate, exposure, and risks. This study predicted water solubility (Sw), vapor pressure (Vp), octanol-water partition coefficient (Kow), and octano ...
Article GUID: 40105294
Author(s): Cheligeer C; Southern DA; Yan J; Wu G; Pan J; Lee S; Martin EA; Jafarpour H; Eastwood CA; Zeng Y; Quan H;
Objectives: Adverse event detection from Electronic Medical Records (EMRs) is challenging due to the low incidence of the event, variability in clinical documentation, and the complexity of data formats. Pulmonary embolism as an adverse event (PEAE) is particularly difficult to identify using exi ...
Article GUID: 40105654
