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Engineered iron-sulfur carriers for efficient mixotrophic and sulfur autotrophic denitrification in low carbon to nitrogen ratio municipal wastewater: Mechanisms of biofilm enhancement and electron transfer promotion

Author(s): Yu S; Zhang X; Guo T; Li H; Liu W; Chen Z; Wang X; Ren B; Guo J;

Sulfur autotrophic denitrification (SAD) offers a sustainable solution for nitrogen removal in low carbon to nitrogen ratio (C/N) municipal wastewater, yet its efficiency and startup time pose significant challenges. To overcome these, we developed iron-sulfur-modified carriers (FeS@MC) and integrated them into an in-situ sequencing batch reactor (S-Fe-SB ...

Article GUID: 40712941


The complex association between bedtime screen use and adult sleep health

Author(s): Vézina-Im LA; Morin CM; Chen S; Ivers H; Carney CE; Chaput JP; Dang-Vu TT; Davidson JR; Robillard R;

Objectives: To evaluate whether bedtime screen use is associated with sleep health and if this association varies by biological sex, age, and income among adults in Canada. Methods: Data were collected through a national stratified random population-based phone interview on sleep health among ad ...

Article GUID: 40713469


Impairing the interaction between Erg11 and cytochrome P450 reductase Ncp1 enhances azoles antifungal activities

Author(s): Li W; Whiteway M; Hang S; Yu J; Lu H; Jiang Y;

Azole effectiveness against candidiasis can be compromised by Candida albicans resistance and tolerance, and unfortunately, few clinically useful compounds can enhance azole antifungal activities. We find that the amino acids V234, F235 and L238 of Erg11 are critical for its interaction with Ncp1, and the Ncp1-Erg11 association is important in azole respo ...

Article GUID: 40707518


Mechanochemistry for Metal-Organic Frameworks and Covalent-Organic Frameworks (MOFs, COFs): Methods, Materials, and Mechanisms

Author(s): Marrett JM; Effaty F; Ottenwaelder X; Frišcic T;

The mechanochemistry of metal-organic frameworks (MOFs) is a well-established field whose development has advanced the understanding and the design of both MOF materials and mechanochemical reactions. This review outlines the close and mutually beneficial interplay of these two fields over the past two decades, including the description of mechanochemical ...

Article GUID: 40708349


Assessing quantitative MRI techniques using multimodal comparisons

Author(s): Carter F; Anwander A; Johnson M; Goucha T; Adamson H; Friederici AD; Lutti A; Gauthier CJ; Weiskopf N; Bazin PL; Steele CJ;

The study of brain structure and change in neuroscience is commonly conducted using macroscopic morphological measures of the brain such as regional volume or cortical thickness, providing little insight into the microstructure and physiology of the brain. In contrast, quantitative Magnetic Reson ...

Article GUID: 40705745


Eutrophication and Warming Drive Algal Community Shifts in Synchronised Time Series of Experimental Lakes

Author(s): Garner RE; Taranu ZE; Higgins SN; Paterson MJ; Gregory-Eaves I; Walsh DA;

Lake ecosystems are increasingly impacted by eutrophication and climate change. Whole-lake experiments have provided ecosystem-scale insights into the effects of freshwater stressors, yet these are constrained to the duration of monitoring programmes. Here, we leveraged multidecadal monitoring records and century-scale paleogenetic reconstructions for exp ...

Article GUID: 40704779


Understanding the experience of adults with dyslexia: a quantitative and qualitative analysis

Author(s): Stark Z; Johnson AP;

Dyslexia is a neurobiological disorder characterized by persistent difficulties in reading, writing and spelling. Studying adults with dyslexia is challenging due to diverse experiences, varying ages of diagnosis and potential comorbidities. This study utilized a mixed-method approach to explore how the timing and occurrence of a dyslexia diagnosis influe ...

Article GUID: 40702374


Intolerance of uncertainty, psychological symptoms, and pain in long-term childhood cancer survivors: a report from the Childhood Cancer Survivor Study

Author(s): Alberts NM; Stratton KL; Leisenring WM; Pizzo A; Lamoureux É; Alschuler K; Flynn J; Krull KR; Jibb LA; Nathan PC; Olgin JE; Stinson JN; Armstrong GT;

Purpose: Intolerance of uncertainty is central to many psychological disorders and may contribute to pain. Despite the uncertainty inherent in childhood cancer survivorship, little is known about intolerance of uncertainty in this population. This study aimed to characterize intolerance of uncert ...

Article GUID: 40699439


Variations in perfusion detectable in advance of microstructure in white matter aging

Author(s): Robinson TD; Sun YL; Chang PTH; Gauthier CJ; Chen JJ;

One of the most promising interventional targets for brain health is cerebral perfusion, but its link to white matter (WM) aging remains unclear. Motivated by existing literature demonstrating links between declining cortical perfusion and the development of WM hyperintensities, we posit that regional WM hypoperfusion precedes deteriorating WM integrity. ...

Article GUID: 40694306


24-hour activity cycle behaviors and gray matter volume in mild cognitive impairment

Author(s): Balbim GM; Boa Sorte Silva NC; Falck RS; Kramer AF; Voss MW; Liu-Ambrose T;

Introduction: The 24-hour activity cycle (24-HAC) includes physical activity (PA), sedentary behavior (SB), and sleep. The 24-HAC composition and brain health relationship in adults with mild cognitive impairment (MCI) remains underexplored. We examined associations between 24-HAC composition and gray matter (GM) volume. Methods: Cross-sectional study in ...

Article GUID: 40693459


Evolution from the physical process-based approaches to machine learning approaches to predicting urban floods: a literature review

Author(s): Md Shike Bin Mazid Anik

Urban flooding has become a growing concern for many cities due to accelerating urbanisation, changing weather, and drainage system aging. Earlier studies of floods have taken primarily the traditional process-based approach to predicting urban floods, offering limited exploration of recent advancements in AI-driven, real-time, and community-integrated ap ...

Article GUID: 40692624


Recovery of phenotypically sorted cells using droplet-digital microfluidics

Author(s): Deng Z; Perry JM; Weiss M; Genth R; Autour A; Merten CA; Shih SCC;

Droplet microfluidics has become a ubiquitous and powerful tool for high-throughput phenotypic screening at the single-cell level. Large numbers of cells can be sorted for a variety of functions, including the secretion of antibodies with tailored properties. The recovery of cells from sorted droplets is still very poor compared to droplet sorting, usuall ...

Article GUID: 40693295


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