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Defects in meiosis I contribute to the genesis of androgenetic hydatidiform moles

Author(s): Rezaei M; Liang M; Yalcin Z; Martin JH; Kazemi P; Bareke E; Ge ZJ; Fardaei M; Benadiva C; Hemida R; Hassan A; Maher GJ; Abdalla E; Buckett W; Bolze PA; Sandhu I; Duman O; Agrawal S; Qian J; Vallian Broojeni J; Bhati L; Miron P; Allias F; ...

To identify novel genes responsible for recurrent hydatidiform moles (HMs), we performed exome sequencing on 75 unrelated patients who were negative for mutations in the known genes. We identified biallelic deleterious variants in 6 genes, FOXL2, MAJIN, KASH5, SYCP2, MEIOB, and HFM1, in patients ...

Article GUID: 39545410


Exploring the Qualitative Experiences of Administering and Participating in Remote Research via Telephone Using the Montreal Cognitive Assessment-Blind: Cross-Sectional Study of Older Adults

Author(s): Dumassais S; Grewal KS; Aubin G; O' Connell M; Phillips NA; Wittich W;

Background: The COVID-19 pandemic caused a drastic shift in the practice of research and clinical services. It has been noted that cognition measured via in-person versus remote methods differ substantially, and it is possible that subjective and experiential differences exist between modalities. Objective: The aim of the study is to explore the percepti ...

Article GUID: 39546346


Amorphous Cu/Fe nanoparticles with tandem intracellular and extracellular electron capacity for enhancing denitrification performance and recovery of co-contaminant suppressed denitrification

Author(s): Fu J; Guo T; Li H; Liu W; Chen Z; Wang X; Guo J;

In this study, a functionally stable insoluble Cu/Fe nanoparticles (Cu/Fe NPs) were synthesized and applied denitrification with different contaminants. The results showed that 50 mg/L Cu/Fe NPs increased NO3--N reduction rate up to 14.3 mg/(L·h) about 3 folds compared with the control system (4.7 mg/(L·h)), and Cu/Fe NPs exhibited excellent restorative e ...

Article GUID: 39542060


Canadian Spine Society: 24th Annual Scientific Conference, Wednesday, February 28 - Saturday, March 2, Fairmont Chateau Whistler, Whistler, B.C., Canada

Author(s): Dionne A; Al-Zakri M; Labelle H; Joncas J; Parent S; Mac-Thiong JM; Miyanji F; Lonner B; Eren A; Cahill P; Parent S; Newton P; Dermott JA; Jaakkimainen L; To T; Bouchard M; Howard A; Lebel DE; Hardy S; Malhotra AK; Dermott J; Thevarajah D; Mathias KDA; Yoon S; Sakhrekar R; Lebel DE; Kim DJ; Hadi ...

No abstract available

Article GUID: 39537311


Peripheral Arterial Disease in Nova Scotia: Increased Prevalence, Low Public Awareness, and Poor Edinburgh Claudication Questionnaire Sensitivity

Author(s): MacLean EA; Fogarty EJ; Peterson BJ; Xu S; Giacomantonio NB;

Background: This study had the following 3 goals: (i) to assess the prevalence of peripheral arterial disease (PAD) in a Nova Scotian population; (ii) to evaluate the validity of the Edinburgh Claudication Questionnaire (ECQ) in a Nova Scotian context; and (iii) to evaluate Nova Scotian public knowledge about PAD. Methods: Participants were recruited fro ...

Article GUID: 39525342


Predictive heating load management and energy flexibility analysis in residential sector using an archetype gray-box modeling approach: Application to an experimental house in Québec

Author(s): Abtahi M; Athienitis A; Delcroix B;

This paper presents a methodology to develop archetype gray-box models and use them in an economic model-based predictive control algorithm to simulate optimal heating load management in response to a newly-introduced static time-of-use tariff for Québec's residential sector, rate Flex-D. The methodology is evaluated through a case study, wherein in s ...

Article GUID: 39507415


Effects of Cognition-based and Affect-based Trust Attitudes on Trust Intentions

Author(s): Gill H; Vreeker-Williamson E; Hing LS; Cassidy SA; Boies K;

Despite decades of research on trust in the workplace, researchers continue to struggle with fundamental questions regarding the conceptualization and measurement of organizational trust. To help clarify this construct, we revisit established trust definitions (Mayer et al. Academy of Management Review, 20(3), 709-734, Mayer et al., Academy of Management ...

Article GUID: 39507389


Immunomodulation of human T cells by microbubble-mediated focused ultrasound

Author(s): Baez A; Singh D; He S; Hajiaghayi M; Gholizadeh F; Darlington PJ; Helfield B;

While met with initial and ground-breaking success targeting blood borne cancers, cellular immunotherapy remains significantly hindered in the context of solid tumors by the tumor microenvironment. Focused ultrasound, in conjunction with microbubbles, has found tremendous potential as a targeted and local drug/gene delivery technique for cancer therapy. T ...

Article GUID: 39502696


On the nature, predictors, and outcomes of work passion profiles: A generalisability study across distinct types of employees

Author(s): Gillet N; Morin AJS; Brault S; Becker M; Verbeke I;

Thus far, little research has adopted a person-centred approach to investigate the nature of work passion profiles. As a result, our understanding of the most commonly occurring combinations of harmonious passion (HP) and obsessive passion (OP) in the workplace remains limited. To achieve a more refined understanding of the nature of these work passion pr ...

Article GUID: 39499627


Position-based visual servoing of a 6-RSS parallel robot using adaptive sliding mode control

Author(s): Zhu N; Xie WF; Shen H;

The trajectory tracking control of parallel robots is challenging due to their complicated dynamics and kinematics. This paper proposes a position-based visual servoing (PBVS) approach for a 6-Revolute-Spherical-Spherical (6-RSS) parallel robot using adaptive sliding mode control in Cartesian space. A photogrammetry sensor C-Track 780 in the eye-to-hand c ...

Article GUID: 39492316


The effectiveness and acceptability of formal versus informal mindfulness among university students with and without recent self-injury: A randomized controlled trial

Author(s): Petrovic J; Mettler J; Böke BN; Rogers MA; Hamza CA; Bloom E; Di Genova L; Romano V; Heath NL;

Mindfulness instruction comprising both formal (FM) and informal (IM) mindfulness practice is increasingly offered to university students. FM involves sustaining attention on thoughts, emotions and bodily sensations through structured practices, while IM involves incorporating mindfulness into da ...

Article GUID: 39489621


A guide to exploratory structural equation modeling (ESEM) and bifactor-ESEM in body image research

Author(s): Swami V; Maïano C; Morin AJS;

Traditionally, assessments of factor validity of body image instruments have relied on exploratory or confirmatory factor analysis. However, the emergence of exploratory structural equation modeling (ESEM), a resurgence of interest in bifactor models, and the ability to combine both models (bifactor-ESEM) is beginning to shape the future of body image res ...

Article GUID: 39492241


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