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Optical Fiber Array Sensor for Force Estimation and Localization in TAVI Procedure: Design, Modeling, Analysis and Validation

Author(s): Bandari N; Dargahi J; Packirisamy M;

Transcatheter aortic valve implantation has shown superior clinical outcomes compared to open aortic valve replacement surgery. The loss of the natural sense of touch, inherited from its minimally invasive nature, could lead to misplacement of the valve in the aortic annulus. In this study, a cylindrical optical fiber sensor is proposed to be integrated w ...

Article GUID: 34450813


A Pathfinder in High-Pressure Bioscience: In Memoriam of Gaston Hui Bon Hoa

Author(s): Davydov DR; Jung C; Petsko GA; Sligar SG; Kornblatt JA;

On 26 July 2020, our colleague and friend Dr [...].

Article GUID: 34440010


Bioprinting of Adult Dorsal Root Ganglion (DRG) Neurons Using Laser-Induced Side Transfer (LIST)

Author(s): Roversi K; Ebrahimi Orimi H; Falchetti M; Lummertz da Rocha E; Talbot S; Boutopoulos C;

Cell bioprinting technologies aim to fabricate tissuelike constructs by delivering biomaterials layer-by-layer. Bioprinted constructs can reduce the use of animals in drug development and hold promise for addressing the shortage of organs for transplants. Here, we sought to validate the feasibility of bioprinting primary adult sensory neurons using a newl ...

Article GUID: 34442487


Feasibility of Pressure-Retarded Osmosis for Electricity Generation at Low Temperatures

Author(s): Abbasi-Garravand E; Mulligan CN;

A membrane-based technique for production of pressure-retarded osmosis (PRO) is salinity gradient energy. This sustainable energy is formed by combining salt and fresh waters. The membrane of the PRO process has a significant effect on controlling the salinity gradient energy or osmotic energy generation. Membrane fouling and operating conditions such as ...

Article GUID: 34436319


Understanding Sensitive Period Effects in Musical Training

Author(s): Virginia B Penhune

Adult ability in complex cognitive domains, including music, is commonly thought of as the product of gene-environment interactions, where genetic predispositions influence and are modulated by experience, resulting in the final phenotypic expression. Recently, however, the important contribution of maturation to gene-environment interactions has become b ...

Article GUID: 34435343


The BigBrainWarp toolbox for integration of BigBrain 3D histology with multimodal neuroimaging

Author(s): Paquola C; Royer J; Lewis LB; Lepage C; Glatard T; Wagstyl K; DeKraker J; Toussaint PJ; Valk SL; Collins DL; Khan A; Amunts K; Evans AC; Dickscheid T; Bernhardt BC;

Neuroimaging stands to benefit from emerging ultrahigh-resolution 3D histological atlases of the human brain; the first of which is 'BigBrain'. Here, we review recent methodological advances for the integration of BigBrain with multi-modal neuroimaging and introduce a toolbox, 'BigBra ...

Article GUID: 34431476


A Multilevel Person-Centered Examination of Teachers' Workplace Experiences: Replication and Extension With Links to Instructional Support and Achievement

Author(s): Collie RJ; Martin AJ; Morin AJS; Malmberg LE; Sammons P;

In a replication and extension of an earlier study, we relied on person-centered analyses to identify teacher (Level 1) and school (Level 2) profiles based on teachers' experiences of job demands (barriers to professional development, disruptive student behavior), job resources (teacher collaboration, input in decision-making), and personal resources ...

Article GUID: 34421763


Dynamic Covalent Polyurethane Network Materials: Synthesis and Self-healability

Author(s): Nellepalli P; Patel T; Oh JK;

Polyurethane (PU) has not only been widely used in our daily lives, but also extensively explored as an important class of the essential polymers for various applications. In recent years significant efforts have been made on the development of self-healable PU materials that possess high performance, extended lifetime, great reliability, and recyclabilit ...

Article GUID: 34418209


Design, structure-activity relationship study and biological evaluation of the thieno[3,2-c]isoquinoline scaffold as a potential anti-cancer agent

Author(s): Liu JT; Jaunky DB; Larocque K; Chen F; Mckibbon K; Sirouspour M; Taylor S; Shafeii A; Campbell D; Braga H; Piekny A; Forgione P;

Several derivatives of a series that share a thienoisoquinoline scaffold have demonstrated potent anti-cancer activity against cancer cell lines A549, HeLa, HCT-116 in the submicromolar concentration range. Structure-activity relationship (SAR) studies on a range of derivatives aided in identifyi ...

Article GUID: 34416378


The effects of evening high-intensity exercise on sleep in healthy adults: A systematic review and meta-analysis

Author(s): Frimpong E; Mograss M; Zvionow T; Dang-Vu TT;

Moderate-intensity exercise is generally recommended for improving sleep, whereas, high-intensity exercise (HIE) prior to bedtime is often discouraged. We conducted a systematic review and meta-analysis to determine if acute or regular (chronic) HIE performed before bedtime disrupts nighttime sleep of healthy adult, good sleepers compared with a no-exerci ...

Article GUID: 34416428


A multiobjective model for the green capacitated location-routing problem considering drivers' satisfaction and time window with uncertain demand

Author(s): Alamatsaz K; Ahmadi A; Mirzapour Al-E-Hashem SMJ;

Location-routing problem is a combination of facility location problem and vehicle routing problem. Numerous logistics problems have been extended to investigate greenhouse issues and costs related to the environmental impact of transportation activities. The green capacitated locating-routing problem (LRP) seeks to find the best places to establish facil ...

Article GUID: 34415526


Modeling of Flame Retardants in Typical Urban Indoor Environments in China during 2010-2030: Influence of Policy and Decoration and Implications for Human Exposure

Author(s): Li Z; Zhu Y; Wang D; Zhang X; Jones KC; Ma J; Wang P; Yang R; Li Y; Pei Z; Zhang Q; Jiang G;

Novel flame retardants (FRs) are of increasing concern, given growing evidence of health effects and use to replace polybrominated diphenyl ethers (PBDEs). This study modeled combined effects of use policies and decoration on indoor FRs and human exposure for 18 widely used PBDEs, organophosphate ...

Article GUID: 34410710


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