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Dual Acidic pH-Responsive Post-Crosslinked E-Spun Nanofibrous Scaffolds Exhibiting Enhanced Disassembly and Release for Localized Cancer Treatment

Authors: Sofia Nieves Casillas-Popova


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Description

The development of multifunctional electro-spun nanofibrous mats has been explored as an effective platform for implantable localized cancer treatment because they provide a supportive matrix to regenerate tissues and deliver encapsulated anticancer drugs to suppress the proliferation of cancer cells. However, conventionally designed nanofibrous scaffolds present several critical challenges, particularly delayed and uncontrolled release of drug molecules due to inefficient crosslinks. Herein, we...

Links

PubMed: https://pubmed.ncbi.nlm.nih.gov/42106934/