Author(s): Wardell JD; Farrelly KN; Moore A; Fox N; Coelho SG; Cunningham JA; O' Connor RM; Hendershot CS;

Background: This study examined motivational pathways between internalizing symptoms (i.e., depression, anxiety, stress) and simultaneous alcohol and cannabis use among young adults. Methods: Participants (N = 151; 64% female, Mean age = 22.07) completed baseline questionnaires assessing interna ...

Article GUID: 40923811

Author(s): Paquette V; Danyluk AJ; Gilbert W; Houle SA; Lavoie P; Eltanoukhi R; Morin AJS;

Young adults use a combination of coping strategies to deal with challenges. Yet, limited research has focused on these combinations, as they differ across different profiles of youth and their implications during the major life transitions of emerging adulthood. Addressing this gap, the present longitudinal person-centered study assesses the nature, stab ...

Article GUID: 40924344

Author(s): Rabouhi N; Guindon S; Coleman EA; van Heesbeen HJ; Greenwood CMT; Lu T; Campeau PM;

Chromodomain Helicase DNA-binding (CHD) proteins compose a family of chromatin remodelers that play crucial roles in DNA repair and gene expression regulation, neural stem cell differentiation and chromatin integrity. Genetic variants in CHD chromatin remodelers are associated with neurodevelopmental disorders with features like autism spectrum disorder a ...

Article GUID: 40907936

Author(s): Bastien L; Cho S; Petrovic J; Khoury B; Bloom E; Heath N;

University students are reporting high levels of stress that interfere with their academic performance and daily functioning. In response, higher education institutions have increasingly implemented digital, self-guided stress management resources to provide students with accessible mental health support. While these interventions show promise for improvi ...

Article GUID: 40895119

Author(s): McGowan AL; Ellison OK; Ham MS; Chandler MC; Pontifex MB;

Purpose: The purpose of the present investigation was to determine the extent to which individuals at the extremes of the aerobic fitness continuum differed in their utilization of arithmetic strategies. Method: Using a cross-sectional design, 37 higher aerobically fit and 37 lower aerobically fit participants completed a complex arithmetic task while ne ...

Article GUID: 40889823

Author(s): Saputra ST; Van Hulst A; Henderson M; Brugiapaglia S; Faustini C; Kakinami L;

Background: A dual-energy x-ray absorptiometry (DXA)-derived phenotype classification based on fat mass and muscle mass has been developed for adults. We extended this to a paediatric population. Methods: Children's (= 17 years) DXA data in NHANES (n = 6120) were used to generate sex- and age-specific deciles of appendicular skeletal muscle mass inde ...

Article GUID: 40878792

Author(s): Karsten M; Gardenghi G; Arruda ACT; Catai AM; Vieira AM; Stein C; de Araujo CLP; Pereira DAG; Matte DL; da Silva FMF; Guimarães FS; Ghisi GLM; Chiappa GRS; Sbruzzi G; Cipriano GFB; Ribeiro GDS; Milani JGPO; Neves LMT; Calegari L; Morais ...

Background: Exercise training is a core component of cardiovascular rehabilitation programs for patients with heart failure (HF). In Brazil, physical therapists frequently deliver rehabilitation interventions. Given heart failure clinical management advancements and varied rehabilitation approach ...

Article GUID: 40857977

Author(s): Pelzer M; Ouellet-Courtois C; Krause S; Coughtrey A; Fink-Lamotte J;

Background: Perceiving a threat as constantly evolving, coming closer and escalating quickly can result in looming vulnerability (LV). LV may be a distal factor in contamination-based OCD (C-OCD) influencing disorder-specific mechanisms such as disgust. The aim of this study was to gain knowledge about three components of LV: speed, proximity and accelera ...

Article GUID: 40858003

Author(s): Semper C; Pham TTM; Ram S; Palys S; Evdokias G; Ouedraogo JP; Moisan MC; Geoffrion N; Reid I; Di Falco M; Bailey Z; Tsang A; Benoit-Gelber I; Savchenko A;

Genomics analysis confirmed the status of filamentous fungi as a rich source of novel secondary metabolites; however, the discovery of these compounds is hampered by the cryptic nature of their biosynthetic pathways under laboratory conditions. Consequently, despite substantial research effort ov ...

Article GUID: 40852424

Author(s): Tremblay SA; Potvin-Jutras Z; Sabra D; Rezaei A; Sanami S; Gagnon C; Intzandt B; Mainville-Berthiaume A; Wright L; Leppert IR; Tardif CL; Steele CJ; Iglesies-Grau J; Nigam A; Bherer L; Gauthier CJ;

Patients with coronary artery disease (CAD) face an increased risk of cognitive impairment, dementia, and stroke. While white matter (WM) lesions are frequently reported in patients with CAD, the effects on WM microstructure alterations remain largely unknown. We aimed to identify WM microstructu ...

Article GUID: 40829939

Author(s): Murphy J; Morais JA; Tsoukas MA; Cooke AB; Daskalopoulou SS; Santosa S;

Introduction: Adipose tissue inflammation, driven in part by immune cells, may contribute to the elevated type 2 diabetes risk in adults with childhood-onset obesity (CO) compared to those with adult-onset obesity (AO). Weight loss can modify adipose tissue immune cell composition, but whether these changes differ by obesity onset remains unknown. Method ...

Article GUID: 40831565