Author(s): Paez A; Gillman SO; Dogaheh SB; Carnes A; Dakterzada F; Barbe F; Dang-Vu TT; Piñol-Ripoll G;

Background: Sleep plays vital roles in brain-health and cognition, including regulating clearance of ß-amyloid (Aß) and tau proteins that hallmark Alzheimer's disease (AD). Changes in sleep physiology can predate cognitive symptoms by decades in AD, but it remains unclear which sleep characte ...

Article GUID: 41452500

Author(s): Páez A; Gillman SO; Dogaheh SB; Carnes A; Dakterzada F; Barbé F; Dang-Vu TT; Ripoll GP;

Introduction: Changes in sleep physiology can predate cognitive symptoms by decades in persons with Alzheimer's disease (AD), but it remains unclear which sleep characteristics predict cognitive and neurodegenerative changes after AD onset. Methods: Using data from a prospective cohort of mild to moderate AD (n = 60), we analyzed non-rapid eye moveme ...

Article GUID: 39878233