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Guide de pratique clinique pour la prise en charge de l obésité chez l enfant

Author(s): Ball GDC; Merdad R; Birken CS; Cohen TR; Goodman B; Hadjiyannakis S; Hamilton J; Henderson M; Lammey J; Morrison KM; Moore SA; Mushquash AR; Patton I; Pearce N; Ramjist JK; Lebel TR; Timmons BW; Buchholz A; Cantwell J; Cooper J; Erdstein ...

id="fra-abstract"> Contexte: L’obésité est une maladie chronique complexe et stigmatisante caractérisée par une accumulation anormale ou excessive de graisse corporelle susceptible de nuire à la santé, d’accroître le risque de complications médicales et de réduire l’espérance de vie des ...

Article GUID: 40721241


A Small Molecule Inhibitor of Erg251 Makes Fluconazole Fungicidal by Inhibiting the Synthesis of the 14α-Methylsterols

Author(s): Lu H; Li W; Whiteway M; Wang H; Zhu S; Ji Z; Feng Y; Yan L; Fang T; Li L; Ni T; Zhang X; Lv Q; Ding Z; Qiu L; Zhang D; Jiang Y;

Fluconazole (FLC) is widely used to prevent and treat invasive fungal infections. However, FLC is a fungistatic agent, allowing clinical FLC-susceptible isolates to tolerate FLC. Making FLC fungicidal in combination with adjuvants is a promising strategy to avoid FLC resistance and eliminate the ...

Article GUID: 36475771


Effects of Transcranial Direct Current Stimulation on Attentional Bias to Methamphetamine Cues and Its Association With EEG-Derived Functional Brain Network Topology

Author(s): Khajehpour H; Parvaz MA; Kouti M; Hosseini Rafsanjani T; Ekhtiari H; Bakht S; Noroozi A; Makkiabadi B; Mahmoodi M;

Background: Although transcranial direct current stimulation (tDCS) has shown to potentially mitigate drug craving and attentional bias to drug-related stimuli, individual differences in such modulatory effects of tDCS are less understood. In this study, we aimed to investigate a source of the in ...

Article GUID: 35380672


Variability in the analysis of a single neuroimaging dataset by many teams.

Author(s): Botvinik-Nezer R, Holzmeister F, Camerer CF, Dreber A, Huber J, Johannesson M, Kirchler M, Iwanir R, Mumford JA, Adcock RA, Avesani P, Baczkowski BM, Bajracharya A, Bakst L, Ball S, Barilari M, Bault N, Beaton D, Beitner J, Benoit RG, Be ...

Nature. 2020 May 20;: Authors: Botvinik-Nezer R, Holzmeister F, Camerer CF, Dreber A, Huber J, Johannesson M, Kirchler M, Iwanir R, Mumford JA, Adcock RA, Avesani P, Baczkowski BM, Bajracharya A, Bakst L, Ball S, Barilari M, Bault N, Beaton D, Beitner J, Benoit RG, Berkers RMWJ, Bhanji JP, Biswa ...

Article GUID: 32483374


Deficiencies in vesicular transport mediated by TRAPPC4 are associated with severe syndromic intellectual disability.

Author(s): Van Bergen NJ, Guo Y, Al-Deri N, Lipatova Z, Stanga D, Zhao S, Murtazina R, Gyurkovska V, Pehlivan D, Mitani T, Gezdirici A, Antony J, Collins F, Willis MJH, Coban Akdemir ZH, Liu P, Punetha J, Hunter JV, Jhangiani SN, Fatih JM, Rosenfel ...

The conserved transport protein particle (TRAPP) complexes regulate key trafficking events and are required for autophagy. TRAPPC4, like its yeast Trs23 orthologue, is a core component of the TRAPP complexes and one of the essential subunits for guanine nucleotide exchange factor activity for Rab ...

Article GUID: 31794024


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