Author(s): Khalifa J; Sulaimon R; Côté-Cyr M; Nguyen PT; Peslherbe G; Bourgault S; Gaudreault R;

Protein misfolding and subsequent aggregation into insoluble amyloid deposits are associated with various diseases, including Alzheimer's disease, systemic amyloidosis, and type 2 diabetes mellitus (T2DM). In T2DM, the peptide hormone islet amyloid polypeptide (IAPP), which regulates glucose homeostasis, aggregates in the pancreas, forming soluble cyt ...

Article GUID: 40768411