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A multimodal neuroimaging study of youth at risk for substance use disorders: Functional magnetic resonance imaging and [18F]fallypride positron emission tomography

Author(s): Nikolic M; Cox SML; Jaworska N; Castellanos-Ryan N; Dagher A; Vitaro F; Brendgen M; Parent S; Boivin M; Côté S; Tremblay RE; Séguin JR; Leyton M;

Background: Adolescent alcohol use is the norm, but only some develop a substance use disorder. The increased risk might reflect heightened mesocorticolimbic responses to reward-related cues but results published to date have been inconsistent. Methods: Young social drinkers (age 18.5 ± 0.6 y.o. ...

Article GUID: 39725679


Cocaine cue-induced mesocorticolimbic activation in cocaine users: Effects of personality traits, lifetime drug use, and acute stimulant ingestion

Author(s): D' Amour-Horvat V; Cox SML; Dagher A; Kolivakis T; Jaworska N; Leyton M;

Stimulant drug-paired cues can acquire the ability to activate mesocorticolimbic pathways and lead to new bouts of drug use. Studies in laboratory animals suggest that these effects are augmented by progressively greater drug use histories, impulsive personality traits, and acute drug ingestion. As a preliminary test of these hypotheses in humans, we expo ...

Article GUID: 34463411


mGlu5 receptor availability in youth at risk for addictions: effects of vulnerability traits and cannabis use.

Author(s): Cox SML, Tippler M, Jaworska N, Smart K, Castellanos-Ryan N, Durand F, Allard D, Benkelfat C, Parent S, Dagher A, Vitaro F, Boivin M, Pihl RO, Côté S, Tremblay RE, Séguin JR, Leyton M

Neuropsychopharmacology. 2020 May 15;: Authors: Cox SML, Tippler M, Jaworska N, Smart K, Castellanos-Ryan N, Durand F, Allard D, Benkelfat C, Parent S, Dagher A, Vitaro F, Boivin M, Pihl RO, Côté S, Tremblay RE, Séguin JR, Leyton M

Article GUID: 32413893


Extra-striatal D2/3 receptor availability in youth at risk for addiction.

Author(s): Jaworska N, Cox SML, Tippler M, Castellanos-Ryan N, Benkelfat C, Parent S, Dagher A, Vitaro F, Boivin M, Pihl RO, Côté SM, Tremblay RE, Séguin JR, Leyton M

Neuropsychopharmacology. 2020 Apr 07;: Authors: Jaworska N, Cox SML, Tippler M, Castellanos-Ryan N, Benkelfat C, Parent S, Dagher A, Vitaro F, Boivin M, Pihl RO, Côté SM, Tremblay RE, Séguin JR, Leyton M

Article GUID: 32259831


Pre-treatment EEG signal variability is associated with treatment success in depression.

Author(s): Jaworska N, Wang H, Smith DM, Blier P, Knott V, Protzner AB

Neuroimage Clin. 2018;17:368-377 Authors: Jaworska N, Wang H, Smith DM, Blier P, Knott V, Protzner AB

Article GUID: 29159049


Effect of GAD1 genotype status on auditory attention and acute nicotine administration in healthy volunteers.

Author(s): Hadjis E, Hyde M, Choueiry J, Jaworska N, Nelson R, de la Salle S, Smith D, Aidelbaum R, Knott V

Hum Psychopharmacol. 2019 Jan;34(1):e2684 Authors: Hadjis E, Hyde M, Choueiry J, Jaworska N, Nelson R, de la Salle S, Smith D, Aidelbaum R, Knott V

Article GUID: 30488987


Effect of (Z)-isomer content on [11C]ABP688 binding potential in humans.

Author(s): Smart K, Cox SML, Kostikov A, Shalai A, Scala SG, Tippler M, Jaworska N, Boivin M, Séguin JR, Benkelfat C, Leyton M

Eur J Nucl Med Mol Imaging. 2019 May;46(5):1175-1178 Authors: Smart K, Cox SML, Kostikov A, Shalai A, Scala SG, Tippler M, Jaworska N, Boivin M, Séguin JR, Benkelfat C, Leyton M

Article GUID: 30607444


Sex differences in [11C]ABP688 binding: a positron emission tomography study of mGlu5 receptors.

Author(s): Smart K, Cox SML, Scala SG, Tippler M, Jaworska N, Boivin M, Séguin JR, Benkelfat C, Leyton M

Eur J Nucl Med Mol Imaging. 2019 May;46(5):1179-1183 Authors: Smart K, Cox SML, Scala SG, Tippler M, Jaworska N, Boivin M, Séguin JR, Benkelfat C, Leyton M

Article GUID: 30627817


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