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Recovery of phenotypically sorted cells using droplet-digital microfluidics

Author(s): Deng Z; Perry JM; Weiss M; Genth R; Autour A; Merten CA; Shih SCC;

Droplet microfluidics has become a ubiquitous and powerful tool for high-throughput phenotypic screening at the single-cell level. Large numbers of cells can be sorted for a variety of functions, including the secretion of antibodies with tailored properties. The recovery of cells from sorted droplets is still very poor compared to droplet sorting, usuall ...

Article GUID: 40693295


Integrating microfluidics and synthetic biology: advancements and diverse applications across organisms

Author(s): Leal-Alves C; Deng Z; Kermeci N; Shih SCC;

Synthetic biology is the design and modification of biological systems for specific functions, integrating several disciplines like engineering, genetics, and computer science. The field of synthetic biology is to understand biological processes within host organisms through the manipulation and regulation of their genetic pathways and the addition of bio ...

Article GUID: 38712893


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