Author(s): Andrade-Gagnon B; Casillas-Popova SN; Oh JK;

Well-defined acid-degradable amphiphilic block copolymers (ABPs) and their nanoassemblies labeled with acid-labile groups have been developed for smart drug delivery, exhibiting controlled/enhanced release of therapeutics in tumoral tissues and endo/lysosomes. In general, controlled polymerization techniques, particularly atom transfer radical polymerizat ...

Article GUID: 40614241

Author(s): Casillas-Popova SN; Lokuge ND; Andrade-Gagnon B; Chowdhury FR; Skinner CD; Findlay BL; Oh JK;

Recent advances in the treatment of chronic wounds have focused on the development of effective strategies for cutting-edge wound dressings based on nanostructured materials, particularly biocompatible poly(vinyl alcohol) (PVA)-based electro-spun (e-spun) nanofibers. However, PVA nanofibers need ...

Article GUID: 38989606

Author(s): Andrade-Gagnon B; Casillas-Popova SN; Jazani AM; Oh JK;

Smart nanoassemblies degradable through the cleavage of acid-labile linkages have attracted significant attention because of their biological relevance found in tumor tissues. Despite their high potential to achieve controlled/enhanced drug release, a systematic understanding of structural factors that affect their pH sensitivity remains challenging, part ...

Article GUID: 38499007